IGF-I (24-41) (Synonyms: Insulin-like Growth Factor I (24-41))
目录号: PL05900 纯度: ≥99%
CAS No. :135861-49-3
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中文名称
IGF-I (24-41)
英文名称
IGF-I (24-41)
英文别名
IGF-I (24-41);L-Threonine,L-tyrosyl-L-phenylalanyl-L-asparaginyl-L-lysyl-L-prolyl-L-threonylglycyl-L-tyrosyl...;L-Threonine,L-tyrosyl-L-phenylalanyl-L-asparaginyl-L-lysyl-L-prolyl-L-threonylglycyl-L-tyrosylglycyl-L-seryl-L-seryl-L-seryl-;L-Threonine,L-tyrosyl-L-phenylalanyl-L-asparaginyl-L-lysyl-L-prolyl-L-threonylglycyl-L-tyrosylglycyl-L-seryl-L-seryl-L-seryl-L-arginyl-L-arginyl-L-alanyl-L-prolyl-L-glutaminyl-;TYR-PHE-ASN-LYS-PRO-THR-GLY-TYR-GLY-SER-SER-SER-ARG-ARG-ALA-PRO-GLN-THR;H2N-TYR-PHE-ASN-LYS-PRO-THR-GLY-TYR-GLY-SER-SER-SER-ARG-ARG-ALA-PRO-GLN-THR-OH;H-TYR-PHE-ASN-LYS-PRO-THR-GLY-TYR-GLY-SER-SER-SER-ARG-ARG-ALA-PRO-GLN-THR;H-TYR-PHE-ASN-LYS-PRO-THR-GLY-TYR-GLY-SER-SER-SER-ARG-ARG-ALA-PRO-GLN-THR-OH;IGF-I FRAG 24-41 HUMAN;INSULIN-LIKE GROWTH FACTOR I FRAGMENT 24-41,HUMAN
Cas No.
135861-49-3
分子式
C88H133N27O28
分子量
2017.16
包装储存
Sealed storage, away from moisturePowder -80°C 2 years;-20°C 1 year
产品详情
IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) 是类胰岛素生长因子 I 24 至 41 的氨基酸片段。IGF-I 是一种 70 个氨基酸的多肽激素,是神经元和神经胶质细胞的营养因子。IGF-I对全身生长激素 (GH) 的活动有重要的作用。IGF-I 具有合成代谢、抗氧化、抗炎和细胞保护作用。IGF-I (24-41) 可以调节躯体生长和行为发育。
生物活性
IGF-I (24-41) (Insulin-like Growth Factor I (24-41)) is amino acids 24 to 41 fragment of IGF-I. IGF-I, a 70 aa polypeptide hormone, is a trophic factor for both neurons and glial cells. IGF-I is partly responsible for systemic growth hormone (GH) activities. IGF-I has anabolic, antioxidant, anti-inflammatory and cytoprotective actions. IGF-I (24-41) regulates somatic growth and behavioral development.
性状
Solid
体内研究(In Vivo)
IGF-I (24-41) (ICV; 200 ng dose; 2 μL; postnatal days 2, 4, and 7) regulates somatic growth and behavioral development.
has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Sealed storage, away from moisturePowder -80°C 2 years;-20°C 1 year
SequenceShortening
YFNKPTGYGSSSRRAPQT
Sequence
Tyr-Phe-Asn-Lys-Pro-Thr-Gly-Tyr-Gly-Ser-Ser-Ser-Arg-Arg-Ala-Pro-Gln-Thr
参考文献
[1]. Puche JE, et al. Human conditions of insulin-like growth factor-I (IGF-I) deficiency. J Transl Med. 2012 Nov 14;10:224.
[2]. D Santucci, et al. IGF-I and IGF-I24-41 but not IGF-I57-70 affect somatic and neurobehavioral development of newborn male mice. Brain Res Bull. 1994;35(4):367-71.
[3]. Dan Meng, et al. In
溶解度数据
In Vitro: H2O : 50 mg/mL (24.79 mM; Need ultrasonic)配制储备液
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1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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