BA 1 TFA is a potent agonist for the bombesin (BB) family of receptors. BA1 binds with high affinity to Bombesin receptor subtype-3 (BRS3), gastrin releasing peptide receptor (GRPR), neuromedin B receptor (NMBR) with IC 50 s of 6, 0.4, 2.5 nM.
性状
Solid
体外研究(In Vitro)
BA1 (0.1 μM) significantly increases FAK tyrosine phosphorylation in BRS-3 transfected NCI-H1299 cells. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Sealed storage, away from moisture and lightPowder -80°C 2 years;-20°C 1 year
SequenceShortening
YQWAV{Bal}HF{Nle}-NH2
Solvent&Solubility
In Vitro:
H2O
Peptide Solubility and Storage Guidelines:1. Calculate the length of the peptide.2. Calculate the overall charge of the entire peptide according to the following table:
参考文献
[1]. Terry W Moody, et al. ML-18 is a non-peptide bombesin receptor subtype-3 antagonist which inhibits lung cancer growth. Peptides. 2015 Feb;64:55-61.