Autocamtide 2|129198-88-5|(Autocamtide II)-陌孚医药/Medlife

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Autocamtide 2 (Synonyms: Autocamtide II)

目录号: PL05776 纯度: ≥98%

CAS No. :129198-88-5

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中文名称	Autocamtide 2
英文名称	Autocamtide 2
英文别名	L-Leucine,L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-a-glutamyl-L-threonyl-L-valyl-L-a-aspartyl-L-alanyl-;Autocamtide 2 trifluoroacetate salt;AUTOCAMTIDE 2;Autocamtide-2 [KKALRRQETVDAL];H-Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu-OH;L-Leucine,L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-a-glutamyl-L-th...;L-Leucine,L-lysyl-L-lysyl-L-alanyl-L-leucyl-L-arginyl-L-arginyl-L-glutaminyl-L-a-glutamyl-L-threonyl-L-valyl-L-a-aspartyl-L-a;LYS-LYS-ALA-LEU-ARG-ARG-GLN-GLU-THR-VAL-ASP-ALA-LEU: KKALRRQETVDAL;Autocamtide-2;Autocamtide II;KKALRRQETVDAL;Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu;8: PN: WO2004009562 PAGE: 49 unclaimed sequence;CAM KINASE II SELECTIVE SUBSTRATE;AUTOCAMTIDE-2-RELATED INHIBITOR PEPTIDE
Cas No.	129198-88-5
分子式	C₆₅H₁₁₈N₂₂O₂₀
分子量	1527.77
包装储存	Sealed storage, away from moisturePowder -80°C 2 years；-20°C 1 year

产品详情	Autocamtide 2是钙/钙调蛋白依赖的蛋白激酶II (CaMKII)的高选择性肽底物。它可以用于测定CaMKII的活力。
生物活性	Autocamtide 2 is a highly selective peptide substrate of calcium/calmodulin-dependent protein kinase II (CaMKII). It can be used in the CaMKII activity assay.
性状	Solid
体外研究(In Vitro)	The Ca/calmodulin dependent protein kinases (CaMKs) are multifunctional serine/threonine kinases whose activity are regulated through Ca signaling. It is multifunctional best known for its critical role in learning and memory. Recent studies demonstrates that high levels of different isoform of CaMK, especially for CaMKII, expresses in several cancers such as lung, breast, prostate and colon cancer. CaMKII phosphorylates nearly 40 different proteins, including enzymes, ion channels, kinases, and transcription factors and plays a critical role in the regulation of proliferation, differentiation and survival of various cancer cells. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Sealed storage, away from moisturePowder -80°C 2 years；-20°C 1 year
SequenceShortening	KKALRRQETVDAL
Sequence	Lys-Lys-Ala-Leu-Arg-Arg-Gln-Glu-Thr-Val-Asp-Ala-Leu
参考文献	[1]. Wang YY, et al. The emerging role of CaMKII in cancer. Oncotarget. 2015 May 20;6(14):11725-34.

溶解度数据	In Vitro: H₂O : 20 mg/mL (13.09 mM; Need ultrasonic)配制储备液

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1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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