4-Hydroxyantipyrine|1672-63-5|(4-Hydroxyphenazone; NSC 174055)-陌孚医药/Medlife

您当前的位置：

4-Hydroxyantipyrine (Synonyms: 4-Hydroxyphenazone; NSC 174055)

目录号: PL05576 纯度: ≥98%

CAS No. :1672-63-5

商品编号	规格	价格	会员价	是否有货	数量
PL05576-100mg	100mg	¥865.45	请登录
PL05576-250mg	250mg	¥1298.18	请登录

Medlife所售产品仅用于科学研究（非临床研究），非药品不可食用，不可用于人体或动物的临床诊断和治疗，我们不为个人提供产品及服务。产品COA等资料，可至下方“质量控制”中下载。

加入购物车在线咨询收藏产品大包装询价

中文名称	4-Hydroxyantipyrine
中文别名	4-羟基安替比林;5-氨基-3-甲基-1-（对硝基苯）吡唑;4-羟基-2,3-二甲基-1-苯基-3-吡唑啉-5-酮;4-羟基-1,5-二甲基-2-苯基-1,2-二氢-3H-吡唑-3-酮
英文名称	4-Hydroxyantipyrine
英文别名	4-Hydroxy-1,5-dimethyl-2-phenyl-1H-pyrazol-3(2H)-one;3H-Pyrazol-3-one,1,2-dihydro-4-hydroxy-1,5-dimethyl-2-phenyl-;4-hydroxy-1,5-dimethyl-2-phenylpyrazol-3-one;4-Hydroxyantipyrine;1,2-dihydro-4-hydroxy-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one;1-Phenyl-2,3-dimethyl-4-hydroxy-5-pyrazolone;1-phenyl-2,3-dimethyl-4-hydroxy-pyrazoline-5-on;4-hydroxy-1,5-dimethyl-2-phenyl-1,2-dihydro-3h-pyrazol-3-one;4-Hydroxy-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one;Antipyrine,4-hydroxy;hydroxy-4 antipyrine;Prestwick_270;NSC 174055;4-hydroxy-1,5-dimethyl-2-phenyl-pyrazol-3-one;1,5-Dimethyl-2-phenyl-4-hydroxy-4-pyrazoline-3-one;2,3-Dihydro-4-hydroxy-1,5-dimethyl-2-phenyl-1H-pyrazol-3-one;Antipyrine, 4-hydroxy;DPZ41NV570;SKVPTPMWXJSBTF-UHFFFAOYSA-N;4-Hydroxyantipyrene;Prestwick3_000030;Prestwick2_000030;Prestwick1_000030;Prestwick0_000030;BSPBio_000099;MLS002154180;SPBio_002020;BPBio1_000109;4-HYDROXYANTIPYRINE;4-HYDROXY-2,3-DIMETHYL-1-PHENYL-3-PYRAZOLIN-5-ONE
Cas No.	1672-63-5
分子式	C₁₁H₁₂N₂O₂
分子量	204.23
包装储存	Powder -20°C 3 years；4°C 2 years

产品详情	4-Hydroxyantipyrine (4-Hydroxyphenazone; NSC 174055) 是安替比林 (Antipyrine, HY-B0171) 的主要代谢产物，可作为生物分布促进剂。4-Hydroxyantipyrine 可增加胞磷胆碱和安替比林在脑内的浓度比分布。
生物活性	4-Hydroxyantipyrine (4-Hydroxyphenazone; NSC 174055) is the major metabolite of Antipyrine (HY-B0171), can be as a biodistribution promoter. 4-Hydroxyantipyrine can increase distribution of concentration ratio of Citicoline and Antipyrine in the brain.
性状	Solid
体外研究(In Vitro)	4-Hydroxyantipyrine increase the tissue-to-plasma concentration ratio of Citicoline in the brain and liver and that of thiopental sodium in the brain, liver, and heart. 4-Hydroxyantipyrine enhances the blood-brain barrier (BBB) permeability of Antipyrine considering to be concerned with the increase of the Kp value of Antipyrine in the brain. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Powder -20°C 3 years；4°C 2 years
参考文献	[1]. Ohkawa Y, et al. Effects of 4-hydroxyantipyrine and its 4-O-sulfate on antipyrine as biodistribution promoter. Biol Pharm Bull. 2001 May;24(5):529-34. [2]. Ohkawa Y, et al. Application of 4-hydroxyantipyrine and acetaminophen O-sulfate as biodistribution promoter. Biol Pharm Bull. 2001 Dec;24(12):1404-10.

溶解度数据	In Vitro: DMSO : 50 mg/mL (244.82 mM; ultrasonic and warming and heat to 60°C)配制储备液

搜索质检报告(COA)

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

相关产品