10,11-Dihydrocarbamazepine (Synonyms: 10,11-二氢卡马西平)
目录号: PL05571 纯度: ≥97%
CAS No. :3564-73-6
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中文名称
10,11-Dihydrocarbamazepine
中文别名
10,11-二氢酰胺咪嗪;双氢卡马西平;10,11-二氢卡马西平标准品;10,11-双氢卡马西平;二氢卡马西平;卡马西平相关物质A USP标准品;卡马西平杂质A;卡马西平杂质A EP标准品;卡马西平杂质A(EP) 标准品;10,11-二氢-5H-二苯并[b,f]氮杂卓-5-甲酰胺;10,11-二氢卡马西平
英文名称
10,11-Dihydrocarbamazepine
英文别名
10,11-Dihydro-5H-dibenzo[b,f]azepine-5-carboxamide;10,11-Dihydro-5H-dibenz[b,f]azepine-5-carboxamide;10,11-Dihydrocarbamazepine;5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide;10,11-Dih;10,11-Dihydro-5-carbamoyl-5H-dibenzazepine;10,11-Dihydro-5H-dibenz(b,f)azepine-5-carboxamide;10,11-Dihydrocarbamazepine,10,11-Dihydro-5H-dibenz[b,f]azepine-5-carboxamide;5H-DIBENZ(b,f)AZEPINE-5-CARBOXAMIDE,10,11-DIHYDRO;EINECS 222-649-0;GP 26-301;Dihydrocarbamazepine;EC017VA9FR;AK146901;10,11-Dihydro-5H-dibenzo(b,f)azepine-5-carboxamide
Cas No.
3564-73-6
分子式
C15H14N2O
分子量
238.28
包装储存
Powder -20°C 3 years;4°C 2 years
产品详情
10,11-Dihydrocarbamazepine 是 Oxcarbazepine 的活性代谢物。10,11-Dihydrocarbamazepine 也是一种有机中间体。Oxcarbazepine 会迅速且几乎完全转化为 10,11-Dihydrocarbamazepine,可能具有抗惊厥功效。
生物活性
10,11-Dihydrocarbamazepine is the active metabolite of Oxcarbazepine. 10,11-Dihydrocarbamazepine also is an intermediate. Oxcarbazepine is rapidly and almost completely converted to 10,11-Dihydrocarbamazepine with probable Anticonvulsant efficacy.
性状
Solid
体外研究(In Vitro)
Oxcarbazepine is metabolized in the liver to its active metabolite, 10,11-Dihydrocarbamazepine. Oxcarbazepine is an antiepileptic drug (AED) used to treat partial seizures as a monotherapy or adjunctive therapy.
10,11-Dihydrocarbamazepine may be used as a reference standard for the determination of 10,11-dihydrocarbamazepine in pharmaceutical formulations by liquid chromatography (LC). has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years;4°C 2 years
参考文献
[1]. Courtney Hunek, et al. Measurement of 10,11-dihydro-10-hydroxy-carbamazepine in serum and plasma by high-performance liquid chromatography. Clin Chem Lab Med. 2008;46(10):1429-33.
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