Halazone|80-13-7|(哈拉宗)-陌孚医药/Medlife

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Halazone (Synonyms: 哈拉宗)

目录号: PL05508 纯度: ≥75%

CAS No. :80-13-7

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中文名称	Halazone
中文别名	哈拉宗;4-(N,N-二氯胺磺酰基)苯甲酸;Halazone 哈拉宗;哈拉腙（双氯胺酸）;双氯胺酸;对(N,N-二氯胺磺酰基)苯甲酸;海氯宗;净水龙
英文名称	Halazone
英文别名	Halazone;4-(N,N-Dichlorosulfamoyl)benzoic acid;P-(N,N-DICHLORO- SULFAMYL)BENZOIC ACID;4-[(dichloroamino)sulfonyl]-benzoic acid;4-dichlorosulfamoyl-benzoic acid;4-Dichlorsulfamoyl-benzoesaeure;Benzoesaeure-(sulfonsaeure-(4)-dichloramid);Gynamide;Halazon;Halozone;PANTOCID;Pantocide;Pantosid;p-Dichlorsulfamid-benzoesaeure;Pentocid;Zeptabs;4-(Dichlorosulfamoyl)benzoic Acid;Cloritines;Pantotsid;p-Sulfondichloramidobenzoic acid;Halazonum;Halazono;Parasulfondichloramido benzoic acid;p-Carboxybenzenesulfondichloroamide;Caswell No. 326;p-(N,N-Dichlorosulfamyl)benzoic acid;p-(N,N-Dichlorosulfamoyl)benzoic acid;Halazonum [INN-Latin];Halazono [INN-Spanish];p-(Dichlorosulfamoyl)benzoic acid;Benzoic acid, 4-[(dichloroamino)sulfonyl]-;SPECTRUM1500324;FT-0616739;Q4344352;Spectrum_000839;HALAZONE [MART.];KBio2_003887;Tox21_111104_1;DTXSID9025370;CAS-80-13-7;SBI-0051400.P003;NSC 60717;HALAZONE [MI];SCHEMBL29353;SR-05000001638-1;C7H5Cl2NO4S;NCGC00091225-03;HY-B1386;p-Sulfondichloramidobenzoic acid;Pentocid; Zeptabs;NSC 60717; Pantocid;BSPBio_002094;Tox21_202519;NCGC00260068-01;NCGC00091225-02;LS-1791;Halazone [INN];KBio1_000683;HMS1920B21;Spectrum4_000569;Tox21_111104;D90842;IDI1_000683;Pharmakon1600-01500324;CHEMBL1368146;Spectrum2_000670;DTXCID205370;NINDS_000683;p-(N,N-Dichlorosulfamyl)benzoic acid, analytical standard, >=70% (TLC);NSC757053;D02446;NCGC00091225-04;SR-05000001638;DivK1c_000683;Kyselina p-N,N-dichlorsulfamoylbenzoova [Czech];H0348;KBioSS_001319;EPA Pesticide Chemical Code 077201;Benzoic acid, p-(dichlorosulfamoyl)-;80-13-7;Halazone (USP/INN);MFCD00045858;NSC-757053;CCRIS 6243;CCG-39876;s6440;W-104247;KBio2_001319;CS-0013119;Kyselina p-N,N-dichlorsulfamoylbenzoova;NSC60717;NCGC00091225-06;Spectrum5_000786;KBio3_001314;WLN: QVR DSWNGG;UNII-G359OL82VB;EINECS 201-253-1;2-11-00-00220 (Beilstein Handbook Reference);HALAZONE [WHO-DD];BRN 2740018;SPBio_000739;Spectrum3_000447;4-[(dichloroamino)sulfonyl]benzoic acid;Pantocid;NCGC00091225-01;HMS502C05;NSC-60717;Benzoic acid, 4-((dichloroamino)sulfonyl)-;AB00052007_02;HALAZONE [USP MONOGRAPH];G359OL82VB;KBioGR_000978;AKOS015891386;XPDVQPODLRGWPL-UHFFFAOYSA-N;HMS2091J07;Halazone [USP:INN];p-Dichlorosulfamoylbenzoic acid;KBio2_006455;halazone
Cas No.	80-13-7
分子式	C₇H₅Cl₂NO₄S
分子量	270.09
包装储存	4°C, sealed storage, away from moistur 该产品在溶液状态不稳定，建议您现用现配，即刻使用。

产品详情	Halazone 是一种非典型的抗菌磺酰胺衍生物，是碳酸酐酶 II (carbonic anhydrase II) 抑制剂，K_d 值为 1.45 µM。Halazone 可保护钠通道免于灭活。Halazone 被广泛用于饮用水消毒。
生物活性	Halazone is an atypical antimicrobial sulfonamide derivative and a carbonic anhydrase II inhibitor with a K d value of 1.45 μM. Halazone protects sodium channels from inactivation. Halazone is widely used for disinfection of drinking water.
性状	Solid
体外研究(In Vitro)	Halazone is chemically closely related to Chloramine-T, the nitrogen atom is linked with two instead of one chlorine atom and, certainly more important here, a methyl group is replaced by a carboxyl group. The effect of Halazone on the sodium current is studied in voltage-clamped single nerve fibers of the frog. The oxidant Halazone drastically inhibits inactivation. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	4°C, sealed storage, away from moistur 该产品在溶液状态不稳定，建议您现用现配，即刻使用。
参考文献	[1]. M Rack, et al. Effects of Some Chemical Reagents on Sodium Current Inactivation in Myelinated Nerve Fibers of the Frog. Biophys J. 1986 Oct;50(4):557-64. [2]. Rema Iyer, et al. Inhibition Profiling of Human Carbonic Anhydrase II by High-Throughput Screening of Structurally Diverse, Biologically Active Compounds. J Biomol Screen. 2006 Oct;11(7):782-91.

溶解度数据	In Vitro: DMSO : 100 mg/mL (370.25 mM; Need ultrasonic)配制储备液

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1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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