Estradiol benzoate-d3
目录号: PL05474
CAS No. :1192354-74-7
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中文名称
Estradiol benzoate-d3
中文别名
苯甲酸雌二醇-D3氘代内标;17Β-雌二醇-16,16,17-D3 3-苯甲酸酯;17Β-雌二醇-16,16,17-[D3]-3-苯甲酸酯
英文名称
Estradiol benzoate-d3
英文别名
17β-Estradiol-16,16,17-d3 3-Benzoate;17β-Estradiol-16?16?17-d3 3-Benzoate
Cas No.
1192354-74-7
分子式
C25H28O3
分子量
376.49
包装储存
Please store the product under the recommended conditions in the Certificate of Analysis.
产品详情
Estradiol benzoate-d3 是 Estradiol benzoate 氘代物。Estradiol Benzoate (β-Estradiol 3-benzoate) 是雌二醇的前体药物,是一种类固醇性激素。Estradiol Benzoate表现出轻微的合成代谢特性,增加血液凝固性。
生物活性
Estradiol benzoate-d 3 is the deuterium labeled Estradiol benzoate. Estradiol Benzoate (β-Estradiol 3-benzoate), a prodrug of estradiol, acts as a steroid sex hormone. It exhibits mild anabolic and metabolic properties, and increases blood coagulability[1][2][3][4].
体外研究(In Vitro)
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
[2]. Zovko M, et al. Macromolecular prodrugs XI. Synthesis and characterization of polymer-estradiol conjugate. Int J Pharm. 2004 Nov 5;285(1-2):35-41.
[3]. García-Gómez E, et al.
搜索质检报告(COA)

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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