Deferiprone-d3|1346601-82-8|(去铁酮 d-陌孚医药/Medlife

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Deferiprone-d3 (Synonyms: 去铁酮 d

目录号: PL05368

CAS No. :1346601-82-8

商品编号	规格	价格	会员价	是否有货	数量
PL05368-5mg	5mg	询价	询价
PL05368-50mg	50mg	询价	询价

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中文名称	Deferiprone-d3
中文别名	[2H3]-DEFERIPRONE;[2H3]-去铁酮;去铁酮 d3
英文名称	Deferiprone-d3
英文别名	Deferiprone-d3;1,2-DiMethyl-3-hydroxypyrid-4-one-d3;3-Hydroxy-1,2-diMethyl-4(1H)-pyridinone-d3;CP-20-d3;DMHP-d3;Kelfer-d3;TZXKOCQBRNJULO-BMSJAHLVSA-N;[2H3]-Deferiprone
Cas No.	1346601-82-8
分子式	C₇H₉NO₂
分子量	139.15
包装储存	Please store the product under the recommended conditions in the Certificate of Analysis.

产品详情	Deferiprone-d₃ 是 Deferiprone 的氘代物。Deferiprone 是唯一口服有活性的铁螯合剂, 用于研究地中海贫血中的输血性铁过载。
生物活性	Deferiprone-d 3 is the deuterium labeled Deferiprone. Deferiprone is the only orally active iron-chelating drug to be used therapeutically in conditions of transfusional iron overload[1][2].
体外研究(In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Kontoghiorghes GJ, et al. Benefits and risks of deferiprone in iron overload in Thalassaemia and other conditions: comparison of epidemiological and therapeutic aspects with deferoxamine. Drug Saf. 2003;26(8):553-584.

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1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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