Procaine hydrochloride|51-05-8|(盐酸普鲁卡因)-陌孚医药/Medlife

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Procaine hydrochloride (Synonyms: 盐酸普鲁卡因)

目录号: PL05363 纯度: ≥99%

CAS No. :51-05-8

商品编号	规格	价格	会员价
PL05363-500mg	500mg	¥494.55	请登录
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PL05363-5g	5g	¥989.09	请登录
PL05363-10g	10g	询价	询价
PL05363-50g	50g	询价	询价

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中文名称	Procaine hydrochloride
中文别名	盐酸普鲁卡因;对氨基苯甲酸-2-二乙胺基乙酯盐酸盐;4-氨基苯甲酸-2-(二乙氨基)乙酯单盐酸盐;2-二乙基氨基乙基4-氨基苯甲酸酯盐酸盐;對胺苯甲酸Β-二乙胺乙酯鹽酸鹽;2-(二乙氨基)乙基4-氨基苯甲酸酯盐酸盐;Procaine Hydrochloride 盐酸普鲁卡因;奥扎格雷钠;奴佛卡因;普鲁卡因;盐酸普鲁卡因BP;盐酸普罗卡因;盐酸左氧氟沙星;4-氨基苯甲酸-2-(二乙氨基)乙酯盐酸;分析对照品;盐酸美托咪定;4-氨基苯甲酸-2-二乙氨乙酯;奴佛卡因盐酸盐;对氨基苯甲酸二乙氨乙酯盐酸盐
英文名称	Procaine hydrochloride
英文别名	Procaine hydrochloride;2-DIETHYLAMINO-4-AMINO-BENZOATE HYDROCHLORIDE;2-DIETHYLAMINOETHYL 4-AMINOBENZOATE HYDROCHLORIDE;2-DIETHYLAMINOETHYL P-AMINOBENZOATE HYDROCHLORIDE;4-AMINO-BENZOIC ACID 2-DIETHYLAMINO-ETHYL ESTER;4-AMINOBENZOIC ACID 2-DIETHYLAMINOETHYL ESTER HYDROCHLORIDE;AKOS B006598;ART-CHEM-BB B006598;NOVOCAINE HYDROCHLORIDE;P-AMINOBENZOIC ACID 2-(DIETHYLAMINO)ETHYL ESTER HYDROCHLORIDE;P-AMINOBENZOIC ACID DIETHYLAMINO-ETHYL ESTER HYDROCHLORIDE;P-AMINOBENZOYLDIETHYLAMINOETHANOL HYDROCHLORIDE;PROCAINE;PROCAINE HCL;PROCAIN HYDROCHLORIDE;TIMTEC-BB SBB001081;aminocaine;anadolor;anesthesol;Procaine (hydrochloride);Mannitol Salt Agar Medium;2-(Diethylamino)ethyl 4-Aminobenzoate Hydrochloride;4-Aminobenzoic Acid 2-(Diethylamino)ethyl Ester Hydrochloride;anestil;cetain;ethocaine;eugerase;irocaine;naucaine;Novocaine;paracain;syncaine;topokain;Vitamin H3;Spinocaine;Duracaine;Procain;Nissocaine;Novocain;2-(Diethylamino)ethyl 4-aminobenzoate;Procaina;Procainum;Procaine, base;2-Diethylaminoethyl p-aminobenzoate;Diethylaminoethyl p-aminobenzoate;Gerovital;Norocaine;Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester;2-Diethylaminoethyl 4-aminobenzoate;p-Aminobenzoyldiethylaminoethanol;Factor H3;p-Aminobenzoic acid 2-diethylaminoethyl ester;Stoff H3;Jenacaine;Jenacain;Procaine [INN:BAN];Procainum [INN-Latin];Proc;SR-01000076096-6;Tox21_110248;Gero;Eugerase;Novocaine HCl;Prestwick_530;SMR000718771;BS-4445;2-(Diethylamino)ethyl p-aminobenzoate monohydrochloride;HY-B0546A;PROCAINE HYDROCHLORIDE [EP IMPURITY];Omnicain;Irocaine;Enpro;NCGC00015864-02;Pharmakon1600-01500504;Benzoic acid, 4-amino-, 2-(diethylamino)ethyl ester, monohydrochloride;AI3-02404;NCGC00094267-04;PROCAINE HYDROCHLORIDE [VANDF];A1163;SP-01A;SR-01000076096-1;BP166251;CCG-39234;Juvocaine;NSC757280;Procaine hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material;PROCAINE HYDROCHLORIDE [ORANGE BOOK];Allocaine;CHEMBL1200841;Procaine (Novocaine) HCl;CAS-51-05-8;51-05-8 (HCl);PROCAINE HYDROCHLORIDE [WHO-DD];Tox21_110248_1;SPECTRUM1500504;PROCAINE HYDROCHLORIDE [MART.];Rocain;4-Aminobenzoic acid 2-(diethylamino)ethyl ester hydrochloride;HMS1568I03;Procaine hydrochloride, United States Pharmacopeia (USP) Reference Standard;LP00966;PROCAINE HYDROCHLORIDE [USP MONOGRAPH];HCBIBCJNVBAKAB-UHFFFAOYSA-N;Westocaine;BIM-0050939.0001;Sevicaine;Q3680934;SCHEMBL27720;Neotonocaine;SW196719-3;Procain HCl;Procaine Hydrochloride 1.0 mg/ml in Acetonitrile (as free base);NCGC00015864-07;Kerocaine;2-diethylaminoethyl 4-aminobenzoate hydrochloride;NCGC00094267-03;UNII-95URV01IDQ;HMS1920L06;Procaine Hcl;AC-14461;Procaine, hydrochloride;Procaine hydrochloride, VETRANAL(TM), analytical standard;Gerovital H3;Syncaine;MLS001336056;Chlorocaine;Medaject;PROCAINE HYDROCHLORIDE [USP-RS];Atoxicocaine;LS-35780;Cetain;EN300-02321;CARDIOPLEGIN COMPONENT PROCAINE HYDROCHLORIDE;D78370;Planocai...
Cas No.	51-05-8
分子式	C₁₃H₂₀N₂O₂
分子量	236.31
包装储存	4°C, sealed storage, away from moisture and light 该产品在溶液状态不稳定，建议您现用现配，即刻使用。

产品详情

Procaine hydrochloride 是 DNA 脱甲基剂。Procaine hydrochloride 通过多个靶标起作用，起效缓慢，作用持续时间短。

生物活性

Procaine hydrochloride is a DNA-demethylating agent. Procaine hydrochloride acts through multiple targets and has a slow onset and a short duration of action.

性状

Solid

体外研究(In Vitro)

Procaine hydrochloride (0.01-100 microM) inhibited the 5-HT3 receptor-mediated inward current in the whole-cell patch clamp recording. Procaine appears to produce a competitive inhibition on 5-HT3 receptors with a KD of 1.7 microM. Procaine is a DNA-demethylating agent that produces a 40% reduction in 5-methylcytosine DNA content as determined by high-performance capillary electrophoresis or total DNA enzyme digestion. Procaine can also demethylate densely hypermethylated CpG islands. Procaine also has growth-inhibitory effects in these cancer cells, causing mitotic arrest. Procaine functions as an excitant of limbic system cells, and that procaine alters synaptic transmission in some, but not all, output pathways from the amygdale. has not independently confirmed the accuracy of these methods. They are for reference on

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture and light 该产品在溶液状态不稳定，建议您现用现配，即刻使用。

ClinicalTrial

参考文献

[1]. Fan, P. and F.F. Weight, Procaine impairs the function of 5-HT3 receptor-ion channel complex in rat sensory ganglion neurons. Neuropharmacology, 1994. 33(12): p. 1573-9.
[2]. Villar-Garea, A., et al., Procaine is a DNA-demethylating agent with growth-inhibitory effects in human cancer cells. Cancer Res, 2003. 63(16): p. 4984-9.

溶解度数据	In Vitro: DMSO : 50 mg/mL (183.30 mM; Need ultrasonic)H₂O : ≥ 50 mg/mL (183.30 mM)

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产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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