Procainamide (Synonyms: Procaine amide; SP 100)
目录号: PL05207 纯度: ≥95%
CAS No. :51-06-9
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中文名称
Procainamide
中文别名
普鲁卡因胺;4-氨基-N-[2-(二乙基氨基)乙基]苯甲酰胺;4-氨基-N-(2-二乙氨基乙基)苯甲酰胺;4-氨基-n-(2-二乙基氨基乙基)苯甲酰胺;普鲁卡因胺; 4-氨基-N-[2-(二乙基氨基)乙基]苯甲酰胺;普鲁卡因胺(分析标准品)
英文名称
Procainamide
英文别名
4-Amino-N-(2-diethylaminoethyl)benzamide;PROCAINEAMIDE;Novocainamide;Novocaine amide;Novocamid;Procamide;Procainamide;4-Amino-N-[2-(diethylamino)ethyl]benzamide;C07401;Biocoryl;Procaine amide;Pronestyl;Novocainamid;Procainamida;Procainamidum;Procan;Procapan (free base);p-Aminobenzoic diethylaminoethylamide;Procanbid;p-Amino-N-(2-diethylaminoethyl)benzamide;Procainamide [INN:BAN];Procapan;Procainamidum [INN-Latin];Procainamida [INN-Spanish];Pronestyl-Sr;4-Amino-N-(2-(diethylamino)ethyl)benzamide;Prestwick2_000337;BB 0216450;4-amino-n-(2-diethylamino-ethyl)-benzamide;HMS553P13;KBio2_000183;Tox21_110246;D08421;KBioSS_000183;NCGC00015859-05;KBioSS_001316;PROCAINAMIDE [HSDB];NCGC00015859-16;2-Diethylaminoethylamid kyseliny p-aminobenzoove;NINDS_000931;CAS-614-39-1;KBio2_003884;L39WTC366D;BRD-K75089421-003-04-7;CHEMBL640;NCGC00015859-03;HMS1361J05;NCGC00015859-14;NCGC00015859-04;4-Amino-N-[2-(diethylamino)ethyl]benzamide #;Benzamide, p-amino-N-(2-(diethylamino)ethyl)-;Spectrum2_001295;cid_66068;NSC27461;KBioGR_000183;SPBio_001329;KBio2_006452;NCGC00024323-06;DTXCID403512;BDBM39344;CS-W009100;UNII-L39WTC366D;KBio2_001316;N-(2-(DIETHYLAMINO)ETHYL)-4-AMINOBENZAMIDE;AB00053530;HSDB 3170;Benzamide, 4-amino-N-[2-(diethylamino)ethyl]-;GTPL4811;Prestwick0_000337;KBio3_000366;51-06-9;KBio3_000365;Benzamide, p-amino-N-[2-(diethylamino)ethyl]-;BSPBio_002229;KBio2_002751;Bio1_000391;Bio2_000183;NCGC00015859-06;NCGC00015859-08;PROCAINAMIDE [VANDF];BPBio1_000411;NCGC00015859-18;Prestwick3_000337;DTXSID7023512;WLN: ZR DVM2N2&2;STK367963;Benzamide, 4-amino-N-(2-(diethylamino)ethyl)-;N-(2-Diethylaminoethyl) 4-aminobenzamide;HMS2089E13;KBio2_005319;Spectrum4_000487;AB00053530-13;HMS1989J05;SCHEMBL15914;Spectrum_000836;KBio1_000931;PROCAINAMIDE;NCGC00015859-01;Sp 100 (pharmaceutical);IDI1_033933;BSPBio_001463;BRD-K75089421-001-02-5;LS-25492;N1-[2-(diethylamino)ethyl]-4-aminobenzamide;D0U5SI;NCGC00024323-03;4-Amino-N-(diethylaminoethyl)benzamide;AB00053530-15;4-{N-[2-(diethylamino)ethyl]carbamoyl}aniline;BIDD:GT0579;Benzamide, 4-amino-N-(2-(diethylamino)ethyl)-(9CI);NSC-27461;Procan (TN);HMS1791J05;SPBio_002294;L001052;Bio1_000880;FS-5697;Q417597;PROCAINAMIDE [WHO-DD];KBioGR_000973;NCGC00015859-07;BRD-K75089421-003-15-3;NCGC00024323-04;CCG-205075;NCGC00015859-09;Maybridge1_004389;HY-A0084A;C75392;Pronestyl (TN);SMP1_000055;procainamid-;DB01035;NCGC00015859-11;DivK1c_000931;CAS-51-06-9;Cambridge id 5144127;NSC 27461;Tox21_110246_1;NCGC00024323-05;C13H21N3O;Epitope ID:135397;Bio2_000663;Procainamide (INN);HMS3402J05;PROCAINAMIDE [INN];4-amino-N-(2-diethylaminoethyl)-benzamide;F2173-1035;NCGC00015859-23;BRN 2214285;SBI-0050968.P004;NCGC00015859-02;4-amino-N-(2-diethylaminoethyl) benzamide;Procanbid (TN);Bio1_001369;4-azanyl-N-[2-(diethylamino)ethyl]benzamide;hydrochloride;IDI1_000931;EINECS 200-078-8;Lopac0_000995;BSPBio_000373;4-amino-N-(2-diethylaminoethy...
Cas No.
51-06-9
分子式
C13H21N3O
分子量
235.33
包装储存
4°C, protect from light In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
产品详情
Procainamide 是一种特异性强效的 DNA 甲基转移酶 1 (DNMT1) 抑制剂。普鲁卡因胺是一种 1A 类抗心律失常药物。Procainamide 具有研究癌症和心律失常的潜力。
生物活性
Procainamide is a specific and potent inhibitor of DNA methyltransferase 1 (DNMT1). Procainamide is a Class 1A antiarrhythmic agent. Procainamide has the potential for the research of cancer and arrhythmias.
性状
Solid
IC50 & Target[1][2]
DNMT1
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
4°C, protect from light In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
ClinicalTrial
参考文献
[1]. Lee BH, et al. Procainamide is a specific inhibitor of DNA methyltransferase 1. J Biol Chem. 2005;280(49):40749-40756.
[2]. Pritchard B, et al. Procainamide. [Updated 2021 Aug 8]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan-.
溶解度数据
In Vitro: DMSO : 50 mg/mL (212.47 mM; Need ultrasonic)配制储备液
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1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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