Chenodeoxycholic Acid-d4|99102-69-9|(CDCA-d-陌孚医药/Medlife

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Chenodeoxycholic Acid-d4 (Synonyms: CDCA-d

目录号: PL05136

CAS No. :99102-69-9

商品编号	规格	价格	会员价	是否有货	数量
PL05136-5mg	5mg	询价	询价
PL05136-50mg	50mg	询价	询价

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中文名称	Chenodeoxycholic Acid-d4
中文别名	脱氧鹅胆酸-2,2,4,4-d4;4-甲基-3,6-二羟基哒嗪;鹅去氧胆2,2,4,4-D4酸;鹅去氧胆酸-2,2,4,4-d4;鹅去氧胆酸-D4;鹅去氧胆酸-D4氘代
英文名称	Chenodeoxycholic Acid-d4
英文别名	Cholan-24-oic-2,2,4,4-d4acid, 3,7-dihydroxy-, (3a,5b,7a)-;Chenodeoxycholic Acid-d4;Chenodiol-d4;A,5;A,7;CDC-d4;Chendol-d4;Chenocol-d4;Chenodeoxycholic acid-2,2,4,4-d4;Fluibil-d4
Cas No.	99102-69-9
分子式	C₂₄H₄₀O₄
分子量	392.57
包装储存	Please store the product under the recommended conditions in the Certificate of Analysis.

产品详情	Chenodeoxycholic Acid-d₄ 是 Chenodeoxycholic Acid 的氘代物。Chenodeoxycholic Acid 是一种疏水初级胆汁酸，能够活化核受体 FXR，该受体与胆固醇代谢有关。
生物活性	Chenodeoxycholic Acid-d 4 is the deuterium labeled Chenodeoxycholic Acid. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.
体外研究(In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Stauffer AT, et al. Chenodeoxycholic acid and deoxycholic acid inhibit 11 beta-hydroxysteroid dehydrogenase type 2 and cause cortisol-induced transcriptional activation of the mineralocorticoid receptor. J Biol Chem. 2002 Jul 19;277(29):26286-92

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