ALDH1A3-IN-1
目录号: PL04032 纯度: ≥98%
CAS No. :1695970-90-1
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中文名称
ALDH1A3-IN-1
英文名称
ALDH1A3-IN-1
英文别名
Benzaldehyde, 3-bromo-4-(dipropylamino)-;ALDH1A3-IN-1
Cas No.
1695970-90-1
分子式
C13H18BrNO
分子量
284.19
包装储存
4°C, protect from light In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
产品详情
ALDH1A3-IN-1 (Compound 14) 是一个有效的 ALDH1A3 抑制剂,其 IC50 值为 0.63 µM,Ki 值为 0.46 µM。ALDH1A3-IN-1 能被用于研究前列腺癌 (prostate cancer)。
生物活性
ALDH1A3-IN-1 (Compound 14) is a potent ALDH1A3 inhibitor, with an IC 50 of 0.63 μM and a K i of 0.46 μM. ALDH1A3-IN-1 can be studied in prostate cancer.
性状
Liquid
IC50 & Target[1][2]
ALDH1A3 0.63 μM (IC50) ALDH1A1 7.08 μM (IC
体外研究(In Vitro)
ALDH1A3-IN-1 (Compound 14) (0-200 μM, 96 h) shows antiproliferative activity in prostate cancer cell lines.
ALDH1A3-IN-1 (0-200 μM, 72 h) reduces cell viability of primary prostate cells in a dose-dependent manner. has not independently confirmed the accuracy of these methods. They are for reference only.Cell Proliferation Assay-tbl">
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
4°C, protect from light In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献
[1]. Ali I M Ibrahim, et al. Expansion of the 4-(Diethylamino)benzaldehyde Scaffold to Explore the Impact on Aldehyde Dehydrogenase Activity and Antiproliferative Activity in Prostate Cancer. J Med Chem. 2022 Mar 10;65(5):3833-3848.
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2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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