4°C, protect from light In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
产品详情
Complement factor D-IN-2 是一种 complement factor D 的抑制剂。Complement factor D-IN-2 在替代补体途径的早期和关键时刻靶向 factor D 并抑制补体级联反应。Complement factor D-IN-2 可用于自身免疫疾病的研究。详细信息请参考专利文献 WO2015130838A1 中的化合物 190。
生物活性
Complement factor D-IN-2 is an inhibitor of complement factor D extracted from patent WO2015130838A1, compound 190. Complement factor D-IN-2 targets factor D and inhibits the complement cascade at an early and essential point in the alternative complement pathway. Complement factor D-IN-2 can be used for the research of autoimmune diseases.
性状
Solid
IC50 & Target[1][2]
complement factor D
体外研究(In Vitro)
Complement factor D-IN-2 reduces the excessive activation of complement factor D. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
4°C, protect from light In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
参考文献
[1]. GADHACHANDA VR, et, al. Aryl, heteroaryl, and heterocyclic compounds for treatment of complement mediated disorders. WO2015130838A1.