ddCTP trisodium 是一类双脱氧核糖核苷酸 (ddNTPs),可作为 DNA 聚合酶链延长抑制剂用于 DNA 测序。ddCTP trisodium 是一种核苷类似物,靶向人类免疫缺陷病毒 (HIV) 的逆转录酶。ddCTP trisodium 可用于艾滋病 (AIDS) 研究。
生物活性
ddCTP trisodium is one of 2,3-dideoxyribonucleoside 5-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. ddCTP trisodium is a nucleoside analog that targets the reverse transcriptase of human immunodeficiency virus (HIV). ddCTP trisodium can be used for AIDS research.
性状
Liquid
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Solution, -20°C, 2 years
参考文献
[1]. Z G Chidgeavadze, et al. 3-Fluoro-2,3-dideoxyribonucleoside 5-triphosphates: terminators of DNA synthesis. FEBS Lett. 1985 Apr 22;183(2):275-8.[2]. Pelletier H, et al. Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP. Science. 1994 Jun 24;264(5167):1891-903.