LASV inhibitor 3.3 is a Lassa fever virus (LASV) inhibitor. LASV inhibitor 3.3 binds with LASV glycoprotein (GP) and promotes virus membrane fusion and infection. LASV inhibitor 3.3 can be used for LASV infection research.
性状
Solid
体外研究(In Vitro)
LASV inhibitor 3.3 (1 nM-100 μM;1 h) 抑制指示病毒糖蛋白假型的鼠白血病病毒 (MLV) 转导,IC50 值为 1.8 μM。LASV inhibitor 3.3 (1 和 10 μM;1 h) 抑制 LAMP1 与 LASV GP 的结合。 has not independently confirmed the accuracy of these methods. They are for reference only.Western Blot Analysis
运输条件
Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years;4°C 2 years
参考文献
[1]. Wang MK, et al. Critical role for cholesterol in Lassa fever virus entry identified by a novel small molecule inhibitor targeting the viral receptor LAMP1. PLoS Pathog. 2018 Sep 28;14(9):e1007322.