11-Ketotestosterone|564-35-2|(11-Oxotestosterone)-陌孚医药/Medlife

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11-Ketotestosterone (Synonyms: 11-Oxotestosterone)

目录号: PL02233 纯度: ≥99%

CAS No. :564-35-2

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中文名称	11-Ketotestosterone
中文别名	11 -酮睾酮;11-氧代睾酮
英文名称	11-Ketotestosterone
英文别名	Androst-4-ene-3,11-dione,17-hydroxy-, (17b)-;(8S,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-2,6,7,8,9,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3,11-dione;11-Keto Testosterone;11-KETOTESTOSTERONE--DEA SCHEDULE III;11-keto-testosterone;11-Oxotestosterone;17beta-Hydroxyandrost-4-ene-3,11-dione;4-Androsten-17;A-Hydroxy-4-androstene-3,11-dione;A-ol-3,11-dione;4-Androsten-17beta-ol-3,11-dione
Cas No.	564-35-2
分子式	C₁₉H₂₆O₃
分子量	302.41
包装储存	-20°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

产品详情	11-Ketotestosterone (11-Oxotestosterone)，是一种氧化形式的 Testosterone，是一种活性雄激素。
生物活性	11-Ketotestosterone (11-Oxotestosterone), an oxidized form of Testosterone, is an active androgen.
性状	Solid
体外研究(In Vitro)	11-Ketotestosterone (11-KT) is a non-aromatizable and the most potent androgen in a few teleost. In vitro, after incubation with 11-Ketotestosterone (10 and 100 μM) for 5 days, both Testosterone and 17β-estradiol concentrations increased in both hepatic explants and ovarian explants culture medium; the concentration of Vitellogenin also increased in hepatic explants culture medium. has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)	In previtellogenic cultured sterlet (Acipenser ruthenus), silastic strips embedded with 11-Ketotestosterone (5 or 25 mg/kg) are implanted in vivo for 30 days. Ovarian masculinization or sex reversal is not observed. 11-Ketotestosterone promotes sterlet ovarian development in a dose-dependent manner. has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	-20°C, sealed storage, away from moistur In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
参考文献	[1]. Wei Wang, et al. Effects of 11-Ketotestosterone on Development of the Previtellogenic Ovary in the Sterlet, Acipenser ruthenus. Front Endocrinol (Lausanne). 2020 Mar 25;11:115. [2]. Yoshitaka Imamichi, et al. 11-Ketotestosterone Is a Major Androgen Produced in Human Gonads. J Clin Endocrinol Metab. 2016 Oct;101(10):3582-3591.

溶解度数据	In Vitro: DMSO : 100 mg/mL (330.68 mM; Need ultrasonic)配制储备液

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2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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