4°C, sealed storage and away from moisture;*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage and away from moisture);
生物活性
L-Palmitoylcarnitine TFA, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine TFA inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2.
性状
Solid
IC50 & Target[1][2]
Human Endogenous Metabolite
体外研究(In Vitro)
L-Palmitoylcarnitine (1 μM) inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2. L-Palmitoylcarnitine simultaneously enhances the ATP sensitivity of the channel (IC50 fell from 62 to 30 μM).Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature or refrigerated transport.
储存方式
4°C, sealed storage and away from moisture;*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage and away from moisture);