ATP disodium salt hydrate (Synonyms: Adenosine 5'-triphosphate disodium salt hydrate)
目录号: PC65711 纯度: ≥98.0%
CAS No. :34369-07-8
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中文名称
ATP disodium salt hydrate
中文别名
腺苷-5'-三磷酸二钠盐,(无钙);腺苷-5'-三磷酸二钠盐,水合物;5′-三磷酸腺苷 (ATP) 二钠盐 水合物;5′-三磷酸腺苷 二钠盐水合物ATP-II;5-腺苷三磷酸二钠盐三水物;5-腺苷三磷酸二钠盐水合物;Adenosine 5'-Triphosphate Disodium Salt Hydrate 腺苷-5'-三磷酸二钠盐水合物;三磷酸腺苷二钠盐;腺苷-5′-三磷酸 二钠盐 水合物;腺苷-5′-三磷酸二钠盐;腺苷-5''-三磷酸二钠盐,(无钙);腺苷-5-三磷酸二钠盐,(无钙);腺苷-5''-三磷酸二钠盐,水合物;5’-三磷酸腺苷二钠,磷酸腺苷钠;5'-三磷酸腺苷二钠盐水合物;ATP二钠盐;ATP二钠盐水合物;三磷酸腺苷二钠;三磷腺苷二钠;腺苷-5’-三磷酸二钠盐,(无钙);腺苷-5’-三磷酸二钠盐,三水;腺苷-5′-三磷酸二钠盐,(无钙);腺苷-5′-三磷酸二钠盐,三水;腺苷-5''-三磷酸二钠盐;腺苷-5'-三磷酸二钠盐,三水;ATP 二钠 水合物;三磷酸腺苷二钠盐水合物;腺苷 5'-三磷酸二钠盐水合物;ATP 二钠盐;ATP 二钠盐 水合物;腺苷-5′-三磷酸二钠盐(无钙)
英文名称
ATP disodium salt hydrate
英文别名
Adenosine5'-(tetrahydrogen triphosphate), disodium salt, hydrate (8CI,9CI);Adenosine 5’-triphosphate disodium salt hydrate;Adenosine 5'-Triphosphate Disodium Salt Hydrate;ADENOSINE 5'-TRIPHOSPHATE DISODIUM SAL&;5′-ATP-Na2;5'-ATP 2Na Hydrate;5'-ATP-Na2;Adenosine 5‘-triphosphate,disodium salt hydrate;Adenosine 5'-triphosphate;Adenosine 5-triphosphate,disodium salt hydrate;ADENOSINE-5'-TRIPHOSPHATE DISODIUM SALT HYDR.,CALCIUM FREE;Adenosine-5'-triphosphate disodium salt hydrate,water;adenosine-5'-triphosphate disodium trihydrate;ATP disodium hydrate;ADENOSINE 5’-TRIPHOSPHATE DISODIUM SAL&;5’-ATP-Na2;ADENOSINE-5’-TRIPHOSPHATE DISODIUM SALT HYDR., CALCIUM FREE;ADENOSINE-5-TRIPHOSPHATE DISODIUM SALT (ATP-Na2) extrapure for biochemistry;5μ-ATP-Na2, ATP hydrate disodium salt;Adenosine-5’-triphosphate disodium salt hydrate, 99+%;5'-ATP,Na2;adenosine-5'-triphosphate disodium salt hydrate;CID 131664345
Cas No.
34369-07-8
分子式
C10H16N5Na2O14P3
分子量
569.16
包装储存
4°C, sealed storage and away from moisture;*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage and away from moisture);
生物活性
ATP disodium salt hydrate (Adenosine 5-triphosphatedisodium salt hydrate) is a central component of energy storage and metabolism in vivo, provides the metabolic energy to drive metabolic pumps and serves as a coenzyme in cells. ATP disodium salt hydrate is an important endogenous signaling molecule in immunity and inflammation.
性状
Solid
IC50 & Target[1][2]
Human Endogenous Metabolite
 
体外研究(In Vitro)
ATP disodium salt hydrate (5mM; 1 hour) co-treatment with LPS (1 μg/ml) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs.
ATP disodium salt hydrate (2 mM; 0.5-24 hours) induces secretion of interleukin 1β, KC and MIP-2 from bone marrow derived macrophages (BMDMs) in vitro in a caspase-1 activation-dependent manner.
ATP disodium salt hydrate stimulats cytokine and chemokine secretion and inflammasome activation directly and indirectly induces in vitro neutrophil chemotaxis.
Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)
ATP disodium salt hydrate (50 mg/kg; i.p.) protects mice against bacterial infection in vivo.
ATP disodium salt hydrate induces the secretion of IL1β, KC and MIP-2 and neutrophils recruitment in vivo.
Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
Animal Model:
运输条件
Room temperature or refrigerated transport.
储存方式
4°C, sealed storage and away from moisture;*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage and away from moisture);
ClinicalTrial
结构分类
Ketones, Aldehydes, Acids
来源
Plants
other fami
溶解度数据
体外研究:
H2O : 100 mg/mL (Need ultrasonic)
体内研究:

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1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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