Sarsasapogenin|126-19-2|(菝葜皂苷元; Parigenin; Sarsagenin)-陌孚医药/Medlife

您当前的位置：

Sarsasapogenin (Synonyms: 菝葜皂苷元; Parigenin; Sarsagenin)

目录号: PC66928 纯度: ≥98%

CAS No. :126-19-2

商品编号	规格	价格	会员价
PC66928-10mg	10mg	¥375.25	请登录
PC66928-25mg	25mg	¥712.50	请登录
PC66928-50mg	50mg	¥1140.00	请登录

Medlife所售产品仅用于科学研究（非临床研究），非药品不可食用，不可用于人体或动物的临床诊断和治疗，我们不为个人提供产品及服务。产品COA等资料，可至下方“质量控制”中下载。

加入购物车在线咨询收藏产品大包装询价

中文名称	Sarsasapogenin
中文别名	菝葜皂苷元;菝葜皂甙元;菝契皂苷;萨洒皂草配基;菝契皂甙元;洋菝契皂甙元;莫哈弗丝兰提取物;菝葜皂甙元: 知母皂苷元;Sarsasapogenin 菝葜皂苷元标准品;菝契皂苷元;菝葜皂甙元(RG);菝葜皂苷元 Sarsasapogenin;菝葜皂苷元（标准品）;菝葜皂苷元,丝兰提取物[茎叶];萨洒皂草配基标准品;丝兰提取物;锗酸铋;知母皂甙元;知母皂苷元;标准品知母皂苷元;对照品;知母皂苷元,Sarsasapogenin,植物提取物,标准品,对照品;菝葜皂苷;菝葜皂苷元/知母皂苷元;知母皂苷元;菝葜皂苷元;菝葜皂苷元
英文名称	Sarsasapogenin
英文别名	Sarsasapogenin;5-BETA, 20-ALPHA, 22-BETA, 25L-SPIROSTAN-3-BETA-OL;[25S]-SPIROSTAN-3BETA-OL;(25s)-spirostan-3b-ol;25S,5ALPHA-SPIROSTAN-3BETA-OL;(25S)-5BETA-SPIROSTAN-3BETA-OL;SASARASAPOGENIN;SARSAPOGENIN;SARSAPOGENINE;SARSASAPOGENIN(RG) PrintBack;Yucca Extract;(25S)-Spirostan-3β-ol;PARIGENIN;PERIGENIN;Sarsagenin;Yucca foam extract;[ "" ];Sarsasapogein;Sarsasapogenenin;CFS802C28F;(3beta,5beta,25S)-spirostan-3-ol;Sarsagenin [INN];sarsasopogenin;cogan;Sarsasapogenine;Sarsasapogenin;;Parigenin;;(25S)-5-beta-spirostan-3-beta-ol;Sarsasapogenin, 95%;Sarsasapogenin, >=98%
Cas No.	126-19-2
分子式	C₂₇H₄₄O₃
分子量	416.64
包装储存	Powder； -20°C； 3 years; 4°C； 2 years；

生物活性	Sarsasapogenin is a sapogenin from the Chinese medical herb Anemarrhena asphodeloides Bunge, with antidiabetic, anti-oxidative, anticancer and anti-inflamatory activities.
性状	Solid
IC50 & Target[1][2]	NF-κB

体外研究(In Vitro)

Sarsasapogenin (20-80 μM) induces apoptosis via caspase-dependent mitochondrial pathway in heLa cells. Sarsasapogenin also induces apoptosis via the caspase-dependent mitochondrial apoptotic pathway. Sarsasapogenin (60 μM)-induced ROS generation triggers ER stress and mitochondrial dysfunction. Sarsasapogenin potently inhibits NF-κB and MAPK activation, as well as IRAK1, TAK1, and IκBα phosphorylation in LPS-stimulated macrophages. Moreover, Sarsasapogenin inhibits the binding of LPS to macrophage Toll-like receptor 4, and polarization of M2 to M1 macrophages.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究(In Vivo)

Sarsasapogenin (20 and 40 mg/kg) significantly restores the sucrose preference deficit induced by olfactory bulbectomy (OB), and increases locomotor activity. Sarsasapogenin groups (20 and 40 mg/kg) have significantly lower immobility times, higher AChE protein expression levels than the OB group. Furthermore, Sarsasapogenin (20 and 40 mg/kg) groups have significantly higher α7-nAChR protein expression, and increases higher α4-nAChR protein expression levels compared to rats in the OB group. Sarsasapogenin (5 or 10 mg/kg, p.o.) inhibits TNBS-induced colon shortening and myeloperoxidase activity in mice, reducing NF-κB activation and interleukin (IL)-1β, tumor necrosis factor (TNF)-α, and IL-6 levels, while simultaneously increasing IL-10.Medlife has not independently confirmed the accuracy of these methods. They are for refere

运输条件

Room temperature or refrigerated transport.

储存方式

Powder； -20°C； 3 years; 4°C； 2 years；

结构分类

Steroids

来源

Plants

溶解度数据	体外研究: Ethanol : 1 mg/mL(2.40 mM;Need ultrasonic) 配制储存液

搜索质检报告(COA)

产品使用指南

Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

相关产品

The molarity calculator equation

The dilution calculator equation