Atropine sulfate monohydrate. (Synonyms: 硫酸阿托品水合物; Tropine tropate sulfate monohydrate; DL-Hyoscyamine sulfate monohydrate)
目录号: PC62921 纯度: ≥99%
CAS No. :5908-99-6
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中文名称
Atropine sulfate monohydrate.
中文别名
硫酸阿托品;硫酸DL-莨菪碱;硫酸颠茄碱;阿托品硫酸单水合物;一水硫酸阿托品;硫酸天仙子胺;顛茄鹼硫酸鹽;alpha-(羟甲基)苯乙酸 8-甲基-8-氮杂双环[3,2,1]-3-辛酯硫酸盐一水合物;硫酸阿托品 GMP;▲硫酸阿托品;硫酸阿托品一水;硫酸阿托品一水物;硫酸阿托品一水合物;WAKO016-11691硫酸阿托品标准品;阿托品 硫酸盐 一水合物;阿托品硫酸盐;颠茄提取物;混旋莨菪碱;硫酸阿托;硫-酸阿托品;硫酸阿托品 标准品;硫酸阿托品、硫酸阿托品一水合物;硫酸阿托品标准品(JP);硫酸阿托品水合物;硫酸阿托品-水物;硫酸阿托品一水 标准品;硫酸阿托品原药;消旋山莨菪碱;一水合硫酸阿托品;一水硫酸阿托品,颠茄提取物[全草];一水硫酸阿托品原药;硫酸颠茄碱,硫酸DL-莨菪碱
英文名称
Atropine sulfate monohydrate
英文别名
Atropine sulfate monohydrate;atropine sulfate crystalline;Atropine sulfate salt monohydrate;Atropine sulphate monohydrate;ATROPINE SULPHATE;Atropine Sulfate;Atropine sulfate hydrate;ATROPINE SULFATE MONOHYDRATE EP6.0;Atropa Belladonnal;atropin sulfate;Atropina Solfato;AtropineSulfat;AtropineSulphateGrPuriss;ATROPINI SULFAS;Atropinsulfat;Atropsiol;Atropt;racemic anisodamine;TROPINI SULFAS;atropine sulfate monohydrate Atropsiol atropine sulfate,monohydrate;alpha-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester sulfate monohydrate;Isopto Atropine;Atropine Sulfate Ansyr Plastic Syringe;Donnagel;atropinum sulphuricum;L-HYOSCYAMINE HEMISULFATE SALT;Atropine sulfate [USP:JAN];1alphaH,5alphaH-Tropan-3alpha-ol (+-)-tropate (ester), sulfate (2:1) (salt) monohydrate;Prestwick_960;Isopto Atropine (TN);alpha-(Hydroxymethyl)benzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester;DSSTox_RID_
Cas No.
5908-99-6
分子式
C34H50N2O11S
分子量
694.83
包装储存
4°C, Sealed and stored away from moisture and light;*In solvent : -80°C, 6 months; -20°C, 1 month (Sealed and stored away from moisture and light);
生物活性
Atropine (Tropine tropate) sulfate monohydrate is a competitive muscarinic acetylcholine receptor (mAChR) antagonist with IC50 values of 0.39 and 0.71 nM for Human mAChR M4 and Chicken mAChR M4, respectively. Atropine sulfate monohydrate inhibits ACh-induced relaxations in human pulmonary veins. Atropine sulfate monohydrate can be used for research of anti-myopia and bradycardia.
性状
Solid
IC50 & Target[1][2]
mAChR4
 
体外研究(In Vitro)
Atropine (Tropine tropate; 1 μM; pulmonary veins and arteries) sulfate monohydrate inhibits ACh-induced relaxations in human pulmonary veins.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)
Atropine (Tropine tropate; 10 mg/kg; i.p.; once, for 40 minutes; Peromyscus sp.) sulfate monohydrate inhibits the cardiac arrhythmia which normally occurs throughout torpor.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
Animal Model:
运输条件
Room temperature or refrigerated transport.
储存方式
4°C, Sealed and stored away from moisture and light;*In solvent : -80°C, 6 months; -20°C, 1 month (Sealed and stored away from moisture and light);
ClinicalTrial
结构分类
Alkaloids
Other A
来源
Plants
溶解度数据
体外研究:
DMSO : 50 mg/mL(143.91 mM;Need ultrasonic)
H2O : 33.33 mg/mL(95.93 mM;Need ultrasonic)
配制储存液
搜索质检报告(COA)

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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