Sucrose (D-(+)-Saccharose) is a disaccharide which is composed of two monosaccharides, glucose and fructose. Sucrose can be applied in some animal models, including metabolic disease, obesity, diet on preference, and diabetes, et al.
性状
Solid
IC50 & Target[1][2]
Human Endogenous Metabolite
体内研究(In Vivo)
Sucrose is a disaccharide which is composed of two monosaccharides, glucose and fructose. Compare to chow-feeding, high-energy (HE)-feeding results in an overall decreased preference for Sucrose solutions in both strains. Specifically, obesity-prone (OP) rats prefer 0.3 M and 1.0 M Sucrose solutions less during HE-feeding relative to chow-feeding (P=0.046 and P=0.012, respectively). As well, obesity-resistant (OR) rats exhibit decreased preferences for 0.01 M, 0.03 M, and 1.0 M Sucrose when HE-fed compare to chow-fed counterparts (P<0.0001, P=0.043, and P=0.013, respectively). Chow-fed OP rats consume significantly less of 0.03 and 0.1 M Sucrose solutions relative to OR animals (P<0.0001, for both) while HE-fed OP rats consume less of a 0.1 M Sucrose solution only (P<0.05), compare to HE-fed OR rats.Medlife has not in