L-Ascorbic acid. (Synonyms: L-抗坏血酸; 维生素C; L-Ascorbate; Vitamin C)
目录号: PC61649 纯度: ≥99%
CAS No. :50-81-7
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中文名称
L-Ascorbic acid.
中文别名
维生素C;丙种维生素;维他命C;抗坏血酸;2,3,4,5,6-五羟基-2-己烯酸-4-内酯;抗坏血酸(维生素C);L-抗坏血酸;维生素C100目;L-(+)-抗坏血酸;L(+)抗坏血酸;L(+)-抗坏血酸;L-(+)-抗坏血酸-(维生素C)(AS);L-(+)-抗坏血酸-(维生素C)(P) (Compendial Traceable);L-(+)-抗坏血酸(维生素C)(RG);L(+)-抗坏血酸标准品;L-(+)-抗坏血酸维生素C;L-Ascorbic Acid L-抗坏血酸;NP D 溶液;包膜维生素C;包衣维生素C;抗坏血酸 (Vitamin C);抗坏血酸 标准品;抗坏血酸 猕猴桃提取物;抗坏血酸 维生素C;抗坏血酸(维生素C) 标准品;抗坏血酸,AR;抗坏血酸,BR;抗坏血酸,GR;抗坏血酸,维生素C EP标准品;色氨酸;食品骨胶;食品级维生素C;水溶性维生素C;维生素 C(L(+)-Ascorbic acid);维生素C (L-抗坏血酸);维生素C (抗坏血酸);维生素C USP BP ER FCC;维生素C USP标准品;维生素C(又名抗坏血酸);维生素C标准品;维生素C粉末;维生素C食品级;针叶樱桃提取物;L-抗坏血;L-抗坏血酸,维他命C,维生素C,丙种维生素,2,3,4,5,6-五羟基-2-己烯酸-4-内酯;VC(抗坏血酸);抗坏血酸标准品(JP);食品;食品营养强化剂;维生素C(中间体);维生素C,抗坏血酸;医药级维生素C粉末;维生素 C(L-抗坏血酸);维生素C ​;L-维生素 C;抗坏血病因子;维生素C 维生素C;维生素C,医药级,纯度:>99%;维生素C包被微丸;维生素 C;维生素C、VC;维生素C 抗坏血酸
英文名称
L-Ascorbic acid
英文别名
L(+)-Ascorbic acid;3-Keto-L-gulofuranolactone;3-Oxo-L-gulofuranolactone;3-oxo-l-gulofuranolactone(enolform);Adenex;Allercorb;Antiscorbic vitamin;Antiscorbutic vitamin;L-(+)-Ascorbic acid;(R)-5-((S)-1,2-Dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one;Ascorbic Acid;Vitamin C;L-ASCORBIC ACID, FREE ACID;Trimethylamine;L-Ascorbate;L-Threoascorbic acid,Antiscorbutic factor,Vitamin C;L-AA;L-Ascorbic acid;L-Threo-2,3,4,5,6-pentahydroxy-1-hexenoic acid-4-lactone;维生素C;VC;Ascorbicap;Cevitamic acid;ascorbate;Ascoltin;Hybrin;Secorbate;Proscorbin;Lemascorb;Ascorteal;Ascorbajen;Testascorbic;Cevitamin;Cetemican;Vitascorbol;Vitamisin;Natrascorb;Citriscorb;Cescorbat;Ascorbutina;Vitacimin;Roscorbic;Laroscorbine;Viscorin;Redoxon;Cenetone;Cegiolan;Cebicure;Ascorvit;Vitacee;Vicelat;Cevimin;Cetamid;Cenolate;Celaskon;Viforcit;Concemin;Cevital;Cergona;Cemagyl;Cebione;Cantaxin;Ascorin;Vitac
Cas No.
50-81-7
分子式
C6H8O6
分子量
176.12
包装储存
4°C, Keep In Dark;*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark);
生物活性
L-Ascorbic acid (L-Ascorbate), an electron donor, is an endogenous antioxidant agent. L-Ascorbic acid inhibits selectively Cav3.2 channels with an IC50 of 6.5 μM. L-Ascorbic acid is also a collagen deposition enhancer and an elastogenesis inhibitor. L-Ascorbic acid exhibits anti-cancer effects through the generation of reactive oxygen species (ROS) and selective damage to cancer cells.
性状
Solid
IC50 & Target[1][2]
Microbial Metabolite
 Human Endogenous Metabolite
 
体外研究(In Vitro)
The anti-cancer effects of L-Ascorbic acid are determined by sodium-dependent vitamin C transporter 2 (SVCT-2), a transporter of L-ascorbic acid. L-Ascorbic acid (0.1 μM-2 mM) exhibits anti-cancer effects according to SVCT-2 expression and L-ascorbic acid uptake. Human colorectal cancer cell lines displays differential responses to L-ascorbic acid, primarily depending on the expression level of SVCT-2.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
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体内研究(In Vivo)
L-Ascorbic acid/Tolbutamide produces hypoglycaemic activity in a dose dependant manner in normal (60 mg/kg) and diabetic (40 mg/kg) condition. In the presence of L-ascorbic acid, Tolbuatmide (20 mg/kg) produces early onset of action and maintained for longer period compared to Tolbutamide matching control.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature or refrigerated transport.
储存方式
4°C, Keep In Dark;*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark);
ClinicalTrial
结构分类
Others
来源
Plants
溶解度数据
体外研究:
DMSO : 100 mg/mL(567.79 mM;Need ultrasonic)
H2O : ≥ 100 mg/mL(567.79 mM)
*≥ means soluble, but saturation unknown.
搜索质检报告(COA)

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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