Acetylcholine chloride.|60-31-1|(氯化乙酰胆碱; ACh chloride)-陌孚医药/Medlife

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Acetylcholine chloride. (Synonyms: 氯化乙酰胆碱; ACh chloride)

目录号: PC61664 纯度: ≥98.0%

CAS No. :60-31-1

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中文名称	Acetylcholine chloride.
中文别名	氯化乙酰胆碱;乙酰氯化胆碱;氯化乙酰胆碱 EP标准品;氯化乙酰胆碱 USP标准品;氯化乙酰胆碱标准品;氯化乙酰氧基三甲基乙铵;(2-羟乙基)乙酰三甲基氯化铵;2-(乙酰氧基)-N,N,N-三甲基乙铵氯化物;氯乙酰胆碱;乙酰基氯化胆碱
英文名称	Acetylcholine chloride
英文别名	Acetylcholine chloride;2-(Acetyloxy)-N,N,N-trimethylethanium chloride;ACH;2-(Acetyloxy)-N,N,N-trimethylethanaminium chloride;ACETYL CHOLINE CHLORIDE ,CP;Acetylcholine chloride,2-(Acetyloxy)-N,N,N-trimethylethanaminiumchloride;ACh chloride;Miochol;Acecoline;Chloroacetylcholine;Arterocoline;Acecholin;Ovisot;Azetylcholinchlorid;MIOCHOL-E;Acetylcholinium chloride;O-Acetylcholine chloride;Choline, chloride acetate;Acetylcholine hydrochloride;2-Acetoxyethyltrimethylammonium chloride;Acetilcolina cloruro [DCIT];Acetylcholini chloridum;Ethanaminium, 2-(acetyloxy)-N,N,N-trimethyl-, chloride;Acetylcholine (chloride);Choline acetate (ester) chlori
Cas No.	60-31-1
分子式	C₇H₁₆ClNO₂
分子量	181.66
包装储存	4°C, Sealed and stored away from moisture and light；*In solvent : -80°C, 6 months; -20°C, 1 month (Sealed and stored away from moisture and light)；

生物活性	Acetylcholine chloride (ACh chloride), a neurotransmitter, is a potent cholinergic agonist. Acetylcholine chloride is a modulator of the activity of dopaminergic (DAergic) neurons through the stimulation of nicotinic acetylcholine receptors (nAChRs). Acetylcholine chloride inhibits p53 mutant peptide aggregation in vitro.
性状	Solid
IC50 & Target[1][2]	Human Endogenous Metabolite

体外研究(In Vitro)

Acetylcholine chloride (ACh chloride; 10 μM) opens the calcium channel and the fluorescence value and intracellular free calcium will increase significantly when the medium is with high calcium, while these will decrease when the medium is without calcium in sweat gland epithelial cells.
Medlife has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究(In Vivo)

Acetylcholine chloride (ACh chloride; SC; 20 mg/kg; single dose) induces pronounced cholinergic stimulation and increase of mouse survival in experimental infection.
Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
Animal Model:

运输条件

Room temperature or refrigerated transport.

储存方式

4°C, Sealed and stored away from moisture and light；*In solvent : -80°C, 6 months; -20°C, 1 month (Sealed and stored away from moisture and light)；

ClinicalTrial

结构分类

Others

溶解度数据	体外研究: H₂O : 100 mg/mL(550.48 mM;Need ultrasonic) DMSO : 62.5 mg/mL(344.05 mM;Need ultrasonic) 配制储存液

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2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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