Ginsenoside Rh2.|78214-33-2|(人参皂苷 Rh2; 20(S)-Ginsenoside Rh2; 20(S)-Rh2; Ginsenoside-Rh2)-陌孚医药/Medlife

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Ginsenoside Rh2. (Synonyms: 人参皂苷 Rh2; 20(S)-Ginsenoside Rh2; 20(S)-Rh2; Ginsenoside-Rh2)

目录号: PC64080 纯度: ≥98%

CAS No. :78214-33-2

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中文名称	Ginsenoside Rh2.
中文别名	人参皂苷 Rh2;人参皂苷-RH2;(R型)人参皂苷RH2;人参皂荚RH2;人参皂苷 S-RH2;人参皂苷RH2(标准品);人参皂甙 Rh2;(20S)人参皂苷 Rh2;(S型)人参皂苷Rh2;20(S)-人参皂苷Rh2;20(S)-人参皂苷-RH2;20(S)-人参皂苷-RH2,20(S)-Ginsenoside-RH2,植物提取物,标准品,对照品;S-人参皂苷Rh2;人参皂甙 Rh2 Ginsenoside Rh2;人参皂苷 Rh2 (S-FORM)(AS);人参皂苷 Rh2 (S-FORM)(P);人参皂苷Rh2 对照品标准品;人参皂苷Rh2 标准品;人参皂苷Rh2（S）;人参皂苷Rh2(人参皂苷S- Rh2 、20(S)-人参皂苷RH2);人参皂苷Rh2对照品;分析对照品
英文名称	Ginsenoside Rh2
英文别名	Ginsenoside Rh2;(3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl beta-d-glucopyranoside;dihydroxydammar-24-en-3-yl;β-D-Glucopyranoside, (3β,12β)-12,20-;R-form-Ginsenoside Rh2;12β,20-Dihydroxy-5α-dammar-24-en-3β-yl β-D-glucopyranoside;3β-(β-D-Glucopyranosyloxy)dammara-24-ene-12β,20-diol;20(S)-Ginsenoside Rh2;20-(S)-GinsenosideRh2;GINSENOSIDE Rh2 (S-FORM)(AS) PrintBack;(3β,12β)-12,20-Dihydroxydammar-24-en-3-yl-β-D-glucopyranoside;20(S)-Rh2;ginenoside Rh2;Ginsenoside-Rh2;20(S)-Ginsenoside-Rh2;2-[[(8R,10R,14R)-12-Hydroxy-17-[(2S)-2-hydroxy-6-methylhept-5-en-2-yl]-4,4,8,10,14-pentamethyl-2,3,5
Cas No.	78214-33-2
分子式	C₃₆H₆₂O₈
分子量	622.87
包装储存	Powder； -20°C； 3 years; 4°C； 2 years；

生物活性	Ginsenoside Rh2 induces the activation of caspase-8 and caspase-9. Ginsenoside Rh2 induces cancer cell apoptosis in a multi-path manner.
性状	Solid
IC50 & Target[1][2]	Caspase-8 Caspase-9
体外研究(In Vitro)	Ginsenoside Rh2 induces the activation of two initiator caspases, caspase-8 and caspase-9 in human cancer cells. Ginsenoside Rh2 induces cancer cell apoptosis in a multi-path manner and is therefore a promising candidate for anti-tumor drug development. Ginsenoside Rh2 triggers p53-dependent Fas expression and consequent activation of caspase-8 and p53-independent caspase-9-mediated intrinsic pathway to cause cancer cell death.The cytotoxic activity of Ginsenoside Rh2 in the human tumor cell lines HeLa, SK-HEP-1, SW480, and PC-3 is assessed by MTT. The cell viability of HeLa cells is remarkably inhibited by Ginsenoside Rh2, with an IC50 value of 2.52 μg/mL, whereas SK-HEP-1 and SW480 cells are less sensitive to Ginsenoside Rh2, with IC50 values of 3.15 μg/mL and 4.06 μg/mL, respectively. PC-3 cells are the least vulnerable to Ginsenoside Rh2, with an IC
体内研究(In Vivo)	A total of 15 days following B16-F10 cell injection, tumor sizes from the 3 tumor bearing groups are measured. The tumor sizes in the G-L group and G-H group (G-L and G-H refer to a low or high dose of ginsenoside Rh2 injection) are reduced compared with the tumor group (P<0.05). The survival analysis reveals that the Ginsenoside Rh2 treated groups survive longer than the untreated tumor group and the effect is dose-dependent (P<0.05).Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件	Room temperature or refrigerated transport.
储存方式	Powder； -20°C； 3 years; 4°C； 2 years；
结构分类	Terpenoids Triter
来源	Plants

溶解度数据	体外研究: DMSO : 50 mg/mL(80.27 mM;Need ultrasonic) 配制储存液

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