hyaluronic acid from bovine vitreous humor;hyaluronic acid sodium from*streptococcus zooepid;Hyaluronic acid from Cockscomb;Hyaluronic Acid;Hyaluronic acid;Hyaluronic Acid from Bovine Vitreous Humor[Substrate for Hyaluronidase] Hyaluronic Acid from Bovine Vitreous Humor [Substrate for Hyaluronidase];HYALURONIC ACID SODIUM SALT;Hyaluronic Acid froM Bovine Vitreous HuMor [Substrate for Hyaluronidase]
Cas No.
9004-61-9
分子式
C28H44N2O23
分子量
776.65
包装储存
4°C, Keep In Dark;*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark);
生物活性
Hyaluronic acid (corn fermented) is a biopolymer composed of repeating units of disaccharides with various applications.
性状
Solid
IC50 & Target[1][2]
Human Endogenous Metabolite
体外研究(In Vitro)
Hyaluronic acid (HA) is widely used in aesthetic medicine due to its binding ability with a large number of water molecules. It improves tissue hydration and their resistance to mechanical damage. HA plays an important role in wound healing, ovulation, fertilization, signal transduction, and tumor physiology. HA is used in joint diseases such as osteoarthritis or rheumatoid arthritis. HA of a high molecular mass reduces the chemotaxis and migration of inflammatory cells which acts as a good barrier to the inflammatory process and protects against the effects of free radicals. HA is used in ophthalmology due to its lubricating properties for the corneal endothelium, and improves tissue hydration and cellular resistance to mechanical damage in aesthetic dermatology, and has marginal adverse effects. Several trials indicate its role in tumor markers, liver diseases, and in pharma
体内研究(In Vivo)
The impact of applied intra-articular HA has been proven in many studies in animals. Studies on HA have shown that it promotes the synthesis of cartilage matrix, prevents its degradation, reduces inflammation, stimulates the synthesis of endogenous HA, and improves the resilience and moisture of cartilage . High molecular size HA preparations, applied topically, promote healing of fresh skin wounds. They also promote the healing of venous leg ulcers and are useful in the management of chronic wounds.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature or refrigerated transport.
储存方式
4°C, Keep In Dark;*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark);
ClinicalTrial
结构分类
SaccharidesPolys
来源
Plants
溶解度数据
体外研究:H2O : 14.29 mg/mL (Need ultrasonic)DMSO : 1 mg/mL (ultrasonic and warming and heat to 80°C)体内研究: