IKarisoside A|55395-07-8|(大花淫羊藿苷 A; Icarisoside-A; Baohuoside II)-陌孚医药/Medlife

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IKarisoside A (Synonyms: 大花淫羊藿苷 A; Icarisoside-A; Baohuoside II)

目录号: PC60527 纯度: ≥99%

CAS No. :55395-07-8

商品编号	规格	价格	会员价	是否有货	数量
PC60527-1mg	1mg	询价	询价

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中文名称	IKarisoside A
中文别名	宝藿苷II;大花淫羊藿苷A;螳晁料闍?II;意卡瑞苷A;大花淫羊藿苷 A
英文名称	IKarisoside A
英文别名	4H-1-Benzopyran-4-one,3-[(6-deoxy-a-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-;8-((2E)-3-Methylbut-2-enyl)-3-((2S,6S,3R,4R,5R)-3,4,5-trihydroxy-6-methylperhydropyran-2-yloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one;Baohuoside II;BAOHUOSIDE Ⅱ;IKarisoside A;Icarisoside-A;Ikarisoside-A;3-[(6-Deoxy-alpha-L-mannopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one;[ "Ikarisoside A" ]
Cas No.	55395-07-8
分子式	C₂₆H₂₈O₁₀
分子量	500.50
包装储存	4°C, Keep In Dark；*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark)；

生物活性	IKarisoside A (Icarisoside-A) is a natural flavonol glycoside and has anti-inflammatory properties.
性状	Solid
体外研究(In Vitro)	Ikarisoside A inhibited the expression of LPS-stimulated inducible nitric oxide synthase (iNOS) and the production of nitric oxide (NO) in LPS-stimulated RAW 264.7 cells and mouse bone marrow-derived macrophages (BMMs) in a concentration-dependent manner. In addition, Ikarisoside A reduced the release of pro-inflammatory cytokines, such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-1 beta (IL-1 beta). Furthermore, Ikarisoside A inhibited the activity of p38 kinase and nuclear factor-kappaB (NF-kappaB). Ikarisoside A is a potent inhibitor of osteoclastogenesis in RANKL-stimulated RAW 264.7 cells as well as in bone marrow-derived macrophages.The inhibitory effect of Ikarisoside A resulted in decrease of osteoclast-specific genes like matrix metalloproteinase 9 (MMP9), tartrate-resistant acid phosphatase (TRAP), receptor activator of NF-kappaB (RANK), and cathep
运输条件	Room temperature or refrigerated transport.
储存方式	4°C, Keep In Dark；*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark)；
结构分类	Flavonoids Flavon
来源	Plants

溶解度数据	体外研究: DMSO : 100 mg/mL(199.80 mM;Need ultrasonic) 配制储存液

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1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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