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Isodeoxyelephantopin (Synonyms: 异去氧苦地胆苦素)
目录号: PC64812 纯度: ≥98.0%
CAS No. :38927-54-7
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中文名称
Isodeoxyelephantopin
中文别名
异去氧苦地胆素;异去氧苦地胆苦素;异山梨醇脱氢酶;异去氧苦地胆苦素标准品对照品;异脱氧高苦地胆内酯
英文名称
Isodeoxyelephantopin
英文别名
2-Propenoic acid, 2-methyl-, (3aR,4S,9S,11E,12aR)-2,3,3a,4,5,9,10,12a-octahydro-11-methyl-3-m ethylene-2,7-dioxo-7H-9,6-methenofuro[2,3-f]oxacycloundecin-4-yl ester;Isodeoxyelephantopin;(2-cyanophenyl)methyl acetate;2-Propenoic acid, 2-methyl-, (3aR,4S,9S,11E,12aR)-2,3,3a,4,5,9,10,12a-octahydro-11-methyl-3-m ethylene-2,7-dioxo-7H-9,6-methe;2-Propenoic acid, 2-methyl-,(3aR,4S,9S,11E,12aR)-2,3,3a,4,5,9,10,12a-octahydro-11-methyl-3-met...;2-Propenoic acid, 2-methyl-,(3aR,4S,9S,11E,12aR)-2,3,3a,4,5,9,10,12a-octahydro-11-methyl-3-methylene-2,7-dioxo-7H-9,6-methenofuro[2,3-f]oxacycloundecin-4-ylester;[(3R,4S,8S,9Z,12R)-10-Methyl-5-methylidene-6,14-dioxo-7,13-dioxatricyclo[10.2.1.04,8]pentadeca-1(15);CID 124593893;Deoxyelephantopin;CID 5281438
Cas No.
38927-54-7
分子式
C19H20O6
分子量
344.36
包装储存
-20°C, Keep In Dark;*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark);
生物活性
Isodeoxyelephantopin is a sesquiterpene lactone isolated from Elephantopus scaber. Isodeoxyelephantopin induces ROS generation, suppresses NF-κB activation. Isodeoxyelephantopin also modulates LncRNA expression and exhibit activities against breast cancer.
性状
Solid
体外研究(In Vitro)
Isodeoxyelephantopin induces protective autophagy in lung cancer cells via Nrf2-p62-keap1 feedback loop.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature or refrigerated transport.
储存方式
-20°C, Keep In Dark;*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark);
结构分类
Terpenoids
Sesqui
来源
Plants
参考文献
[1]. Verma SS, et al. Isodeoxyelephantopin, a Sesquiterpene Lactone Induces ROS Generation, Suppresses NF-κB Activation, Modulates LncRNA Expression and Exhibit Activities Against Breast Cancer. Sci Rep. 2019 Nov 29;9(1):17980.
[2]. Yunna Kim, et al. Treatment of Hominis placenta pharmacopuncture for a patient with mild neurocognitive disorder: Case report. J Pharmacopuncture. 2019 Dec; 22(4): 279–283.
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1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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