Dopamine hydrochloride.|62-31-7|(盐酸多巴胺; ASL279)-陌孚医药/Medlife

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Dopamine hydrochloride. (Synonyms: 盐酸多巴胺; ASL279)

目录号: PC58247 纯度: ≥99%

CAS No. :62-31-7

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中文名称	Dopamine hydrochloride.
中文别名	盐酸多巴胺;3-羟基酷胺盐酸盐;3-羟酪胺;多巴胺盐酸盐;儿茶酚乙胺;儿茶酚乙胺盐酸盐;3-羟基酪胺盐酸盐;3,4-二羟基-Β-苯基乙胺盐酸盐;Dopamine hydrochloride；盐酸多巴胺;多巴胺(盐酸多巴胺)甲醇溶液标准物质;多巴胺及其稳定同位素系列产品;多巴胺盐酸盐,BR;甲醇中多巴胺(盐酸多巴胺)溶液标准物质;酒石酸去甲肾上腺素杂质C;盐酸多巴胺 CP2000;盐酸多巴胺 EP标准品;盐酸多巴胺 USP标准品;盐酸多巴胺标准品;4-(2-氨基乙基)-1,2-苯二酚盐酸盐;4-(2-氨基乙基)-1,2-苯二酚盐酸盐；3-羟基酪胺盐酸盐;去甲肾上腺素杂质C(EP) 标准品;盐酸多巴酚丁胺杂质A(EP);2-(3,4-二羟基苯基)乙胺盐酸盐;3,4-二羟基苯乙胺盐酸盐;4-(2-氨乙基)-1,2-苯二醇盐酸盐;羟酪胺盐酸盐
英文名称	Dopamine hydrochloride
英文别名	4-(2-Aminoethyl)benzene-1,2-diol hydrochloride;2-benzenediol,4-(2-aminoethyl)-hydrochloride;4-(2-aminoethyl)-pyrocatechohydrochloride;dopaminechloride;intropin;m-hydroxytyraminehydrochloride;p498;DOPAMINE HCL;3-Hydroxytyramine hydrochloride;(Dopamine HCl);ASL279;DOPAMINE HCL(RG);Dopamine hydrochloride;Dopamine hydrochloride solution;2-(3,4-Dihydroxyphenyl)ethylamine hydrochloride;4-(2-Aminoethyl)-1,2-benzenediol hydrochloride;3,4-Dihydroxyphenethylamine hydrochloride;4-(2-Aminoethyl)benzene-1;dopamine;4-(2-Aminoethyl)benzene-1,2-diol;Oxytyramine;Hydroxytyramin;Dopamin;3-Hydroxytyramine;3,4-dihydroxyphenethylamine;Dopaminum;Dophamine;2-(3,4-dihydroxyphenyl)ethylamine;4-(2-Aminoethyl)catechol;hydroxytyramine;Dopamina;4-(2-Aminoethyl)pyrocatechol;4-(2-Aminoethyl)-1,2-benzenediol;3,4-Dihydroxyphenylethylamine;L-DOPAMINE;Pyrocatechol, 4-(2-aminoethyl)-;Dopaminum [INN-Latin];1,2-Benzenediol, 4-(2-aminoethyl)-;Dopamina [INN-Spanish];ASL 279;Dopamine [INN:BAN];3-Hydroxtyrami
Cas No.	62-31-7
分子式	C₈H₁₁NO₂
分子量	153.18
包装储存	4°C, Keep In Dark, stored under nitrogen；*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark, stored under nitrogen)；

生物活性	Dopamine hydrochloride (ASL279) is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain. Dopamine hydrochloride (ASL279) plays several important roles in the brain and body. Dopamine hydrochloride (ASL279) acts through D2 dopamine receptors to induce endocytosis of VEGFR2, which is critical for promoting angiogenesis.
性状	Solid
IC50 & Target[1][2]	Human Endogenous Metabolite Microbial Metabolite
体外研究(In Vitro)	Vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) strongly stimulates human umbilical vein endothelial cells (HUVECs) proliferation. The stimulatory effect of VPF/VEGF is abrogated by Dopamine (1 μM; 24hours).Medlife has not independently confirmed the accuracy of these methods. They are for reference only. ass="cpd-vitro-list"> Cell Proliferation Assay-vv-tbl">
体内研究(In Vivo)	Dopamine (50 mg/kg; i.p. injection; days 1-7) strongly and selectively inhibits the vascular permeabilizing and angiogenic activities of VPF/VEGF.Medlife has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model:
运输条件	Room temperature or refrigerated transport.
储存方式	4°C, Keep In Dark, stored under nitrogen；*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark, stored under nitrogen)；
结构分类	Phenols Polypheno

溶解度数据	体外研究: DMSO : 50 mg/mL(263.66 mM;Need ultrasonic) H₂O : ≥ 50 mg/mL(263.66 mM) *≥ means soluble, but saturation unknown.

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1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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