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Eriodictyol (Synonyms: 圣草酚; Huazhongilexone)
目录号: PC58553 纯度: ≥99%
CAS No. :552-58-9
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中文名称
Eriodictyol
中文别名
圣草酚;(S)-2-(3,4-二羟基苯基)-2,3-二氢-5,7-二羟基-4-香豆素;(S)-圣草酚;圣草酚 北美圣草素;圣草酚,Eriodictyol,植物提取物,标准品,对照品;圣草酚对照品;3',4',5,7-四羥二氫黃酮;圣草酚,Eriodictyol;圣草酚,北美圣草素
英文名称
Eriodictyol
英文别名
Eriodictyol;(S)-2-(3,4-Dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-4-benzopyrone;4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-, (2S)-;ERIODICTYOL(SH);riodictyol;(S)-3′,4′,5,7-Tetrahydroxyflavanone;Eriodictiol;Huazhongilexone;[ "" ];(S)-Eriodictyol;(S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxychroman-4-one;(2S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-chromen-4-one;Q520486B8Y;3',4',5,7-Tetrahydroxyflavanone;eryodictiol;eriodicryol;(+)-Eriodictyol;Eriodictyol with HPLC;BIDF1031;BIDF1032;Eriodictyol, analytical standard;2-
Cas No.
552-58-9
分子式
C15H12O6
分子量
288.25
包装储存
4°C, Keep In Dark;*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark);
生物活性
Eriodictyol is a flavonoid isolated from the Chinese herb, with antioxidant and anti-inflammatory activity. Eriodictyol induces Nrf2 signaling pathway. Eriodictyol is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 18 nM.
性状
Solid
IC50 & Target[1][2]
Nrf2
体外研究(In Vitro)
Eriodictyol is a flavonoid isolated from the Chinese herb, with antioxidant and anti-inflammatory activity. Eriodictyol (20, 40, 80 μM) protects primary cultured cortical neurons against Aβ25-35-induced cytotoxicity and cell apoptosis via the Nrf2/ARE pathway. Eriodictyol (80 μM) induces nuclear expression of Nrf2 and the expression of ARE-regulated genes in primary cultured cortical neurons.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
体内研究(In Vivo)
Eriodictyol shows protective effect against LPS-induced acute lung injury (ALI). Eriodictyol (30 mg/kg, p.o.) decreases the production of inflammatory cytokines, elevates survival rate, and decreases oxidative stress levels in LPS-induced ALI mice. Eriodictyol inhibits MPO activity and inflammatory neutrophil accumulation in the lung tissues. Eriodictyol treatment also enhances Trx1 expression by upregulating the Nrf2 expression in lung tissues.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature or refrigerated transport.
储存方式
4°C, Keep In Dark;*In solvent : -80°C, 6 months; -20°C, 1 month (Keep In Dark);
结构分类
Flavonoids
Flavon
来源
Plants
other fami
溶解度数据
体外研究:
DMSO : 125 mg/mL(433.65 mM;Need ultrasonic)
H2O : 0.1 mg/mL(0.35 mM;ultrasonic and warming and heat to 80°C)
配制储存液
搜索质检报告(COA)

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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