Piceatannol (Synonyms: 白皮杉醇; Astringenin; trans-Piceatannol)
目录号: PC58152 纯度: 10mM*1mL in DMSO
CAS No. :10083-24-6
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中文名称
Piceatannol
中文别名
白皮杉醇;(E)-4-[2-(3,5-二羟基苯)乙烯基]-1,2-苯二酚;3,4,3',5'-四羟基-反式-二苯乙烯;比杉特醇;(E)-3,3',4,5'-四羟基苯乙烯;3'-羟基白藜芦醇;4-[2-(3,5-二羟基苯基)乙烯基]-1,2-苯二酚;Piceatannol 白皮杉醇;白皮杉醇;比杉特醇;比杉特醇;Piceatannol
英文名称
Piceatannol
英文别名
trans-Piceatannol;TRANS-3,3',4,5'-TETRAHYDROXYSTILBENE;PICEATANNOL;(e)-4-[2-(3,5dihydroxyphenyl)ethenyl]1,2-benzenediol;4-[2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol;(E)-3,3',4,5'-Tetrahydroxystilbene;(E)-Piceatannol;Astringenin;(E)-4-(3,5-Dihydroxystyryl)benzene-1,2-diol;3,3',4,5'-Tetrahydroxy-trans-stilbene;3,3′,4,5′-Stilbenetetrol;3,3′,4,5′-Tetrahydroxy-trans-stilbene;3,4,3',5'-Tetrahydroxy-trans-stilbene;3;3-Hydroxyresveratol;astringinin;piceatanol;3,5,3',4'-Tetrahydroxystilbene;3,3',4'5-Tetrahydroxystilbene;4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol;3,3',4,5'-Tetrahydroxystilbene;6KS3LS0D4F;3,3',4,5'-Stilbenetetrol;4-[(E)-2-(3,5-dihydroxyphenyl)vinyl]benzene-1,2-diol;1,2-Benzenediol, 4-(2-(3,5-dihydroxyphenyl)ethenyl)-, (E)-;C14H12O4;NSC365798;MFC
Cas No.
10083-24-6
分子式
C14H12O4
分子量
244.24
包装储存
Powder; -20°C; 3 years; 4°C; 2 years;
生物活性
Piceatannol is a well-known Syk inhibitor and reduces the expression of iNOS induced by TNF. Piceatannol is an effective agent for research of acute lung injury (ALI). Piceatannol is a naturally occurring polyphenolic stilbene found in various fruits and vegetables and exhibits anticancer and anti-inflammatory properties. Piceatannol induces apoptosis in DLBCL cell lines. Piceatannol induces autophagy and apoptosis in MOLT-4 human leukemia cells.
性状
Solid
体外研究(In Vitro)
Piceatannol is a resveratrol metabolite.
SYK inhibitor Piceatannol (3.125, 6.25, 12.5, 25, and 50 μM; 72 hours) inhibits cell growth of six diffuse large B cell lymphomas (DLBCL) cell lines (SUDHL-6, U2392,DOHH2,Karpas 422, VAL, OCI Ly19) with IC50s of 18 μM, 25 μM, 37 μM, 48 μM, >50 μM and >50 μM, respectively.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Cytotoxicity Assay

体内研究(In Vivo)
Piceatannol (10, 20, and 40 mg/kg) inhibits the pulmonary edema andreduces the infiltration of inflammatory cells induced by lipopolysaccharide.
Piceatannol (10, 20, and 40 mg/kg) alleviates the myeloperoxidase activity andinhibits the production of iNOS and COX-2 expressions in lung tissuesinduced by lipopolysaccharide.
Piceatannol (10, 20, and 40 mg/kg; intraperitoneally 1 h) treatment alleviates inflammatory response by inhibiting the activation of TLR/NF-κB signaling pathway in lung tissues during acute lung injury (ALI) induced by LPS.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
运输条件
Room temperature or refrigerated transport.
储存方式
Powder; -20°C; 3 years; 4°C; 2 years;
结构分类
Stilbenes
来源
Plants
溶解度数据
体外研究:
DMSO : ≥ 31 mg/mL(126.92 mM)
H2O : 1 mg/mL(4.09 mM;Need ultrasonic)
*≥ means soluble, but saturation unknown.
搜索质检报告(COA)

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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