购物车0
产品总数：60957
| 中文名称 |
L-Tyrosine
|
|---|---|
| 中文别名 |
L-酪氨酸;(2S,3R)-2-氨基-3-对羟苯基丙酸;L-TYROSINE L-酪氨酸;L-酪氨酸,细胞培养级;L-(-)-酪氨酸;DL-亮氨酸;L-(-)-Tyrosine L-(-)-酪氨酸;L-酪氨酸 USP标准品;L-酪氨酸 标准品;L-酪氨酸(RG);L-酪氨酸(食品级)（CP2010）;L-酪氨酸,AR;L-酪氨酸,BR用于细胞培养;L-酪氨酸,非动物源;L-酪氨酸13C9;TY松香E, L-(P);结晶硫酸铜;酪氨酸;酪氨酸 EP标准品;酪氨酸,L-Tyrosine,植物提取物,标准品,对照品;酪氨酸标准品(JP);(S)-2-氨基-3-对羟;L-Β-对羟苯基-Α-氨基丙酸;L-β-对羟苯基-β-丙氨酸;L-Β-对羟基苯基丙氨酸;L-β-对羟基苯基丙氨酸,L-苯酚氨基丙酸,L-β-对羟苯基-α-氨基丙酸,L-干酪氨基酸;L-苯酚氨基丙酸;L-干酪氨基酸;L-酪氨酸,L-Tyrosine;左旋多巴杂质B(EP) 标准品;(S)-2-氨基-3-对羟苯基丙酸;3-(4-对羟苯基)-L-丙氨酸;L-酪氨酸,医药级,纯度:>99%
|
| 英文名称 |
L-Tyrosine
|
| 英文别名 |
L-Tyrosine;3-(4-Hydroxyphenyl)-L-alanine;H-Tyr-OH;L-tyrosine free base cell culture*tested;L-tyrosine plant cell culture tested;L-Tyrosine, Free Base;tyrosine usp;Tyr;L-(-)-Tyrosine;(2S)-2-Amino-3-(4-hydroxyphenyl)propanoic acid;TYROSINE, L-(RG);(S)-2-AMino-3-(4-hydroxyphenyl)propionic acid;LOVALIP;LOVASTIN;L-α-AMino- p-hydroxyhydrocinnaMic acid;L-α-AMino-β-p-hydroxyphenylpropionic acid;MEVACOR;MEVINOLIN;mevlor;msd803;Paschol;Rovacor;Sivlor;2-Amino-3-(4-hydroxyphenyl)-propanoic acid;tyrosine;(S)-Tyrosine;p-Tyrosine;L-p-Tyrosine;4-Hydroxy-L-phenylalanine;Tyrosinum [Latin];Tyrosine (VAN);Tirosina [Spanish];L-Phenylalanine, 4-hydroxy-;(-)-alpha-Amino-p-hydroxyhydrocinnamic acid;Tyrosine [USAN:INN];beta-(p-Hydroxyphenyl)alanine;Tyrosine, L-;(S)-alpha-Amino-4-hydroxybenzenepropanoic acid;L-Tyrosin;L-2-Amino-3-p-hydroxyphenylpropanoic acid;(S)-3-(p-Hydroxyphenyl
|
| Cas No. |
60-18-4
|
| 分子式 |
C9H11NO3
|
| 分子量 |
181.19
|
| 包装储存 |
Powder； -20°C； 3 years; 4°C； 2 years；
|
| 生物活性 |
L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
|
|---|---|
| 性状 |
Solid
|
| IC50 & Target[1][2] |
Microbial Metabolite Human Endogenous Metabolite
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| 体外研究(In Vitro) |
L-Tyrosine inhibits citrate synthase activity in the posterior cortex (2.0 and 4.0 mM), malate dehydrogenase is not altered by L-Tyrosine and succinate dehydrogenase is increased in the posterior cortex (0.1-4.0 mM), hippocampus (1.0-4.0 mM), striatum (4.0 mM) and liver (0.1-4.0 mM). When complex I activity is analyzed, inhibition is observed in hippocampus (4.0 mM). In addition to inhibition in the hippocampus, complex II also is inhibited in the posterior cortex (0.1-4.0 mM) and liver (1.0, 2.0 and 4.0 mM). For complex II–III, activity is not altered by L-Tyrosine, and complex IV activity has decreased in the posterior cortex (1.0-4.0 mM) following treatment with L-Tyrosine.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
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| 体内研究(In Vivo) |
The acute administration of L-Tyrosine inhibits the activity of citrate synthase in the posterior cortex and liver; however, in the striatum, the activity is increased. The results also demonstrate that acute administration of L-Tyrosine inhibits malate dehydrogenase and complex II, II–III and IV of the mitochondrial respiratory chain activity in the posterior cortex and liver of rats. The succinate dehydrogenase enzyme and complex I activity are inhibited in the posterior cortex and increased in the striatum. Furthermore, energy metabolism in the hippocampus is not amended by an acute administration of L-Tyrosine.Medlife has not independently confirmed the accuracy of these methods. They are for reference only.
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| 运输条件 |
Room temperature or refrigerated transport.
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| 储存方式 |
Powder； -20°C； 3 years; 4°C； 2 years；
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| ClinicalTrial |
|
| 结构分类 |
Amino acids
|
| 溶解度数据 |
体外研究:1M HCl : 50 mg/mL(275.95 mM;Need ultrasonic)DMSO : 1 mg/mL(5.52 mM;Need ultrasonic)配制储存液
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|---|
1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。
2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。
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