LY 78335|39959-66-5|-陌孚医药/Medlife

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LY 78335

目录号: PC12585 纯度: ≥98%

CAS No. :39959-66-5

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中文名称

LY 78335

英文名称

1-(2,3-Dichlorophenyl)ethanamine hydrochloride

英文别名

(+/-)-2,3-DICHLORO-ALPHA-METHYLBENZYLAMINE HYDROCHLORIDE;1-(2,3-dichlorophenyl)ethanamine,hydrochloride;LY 78335;LY 78335 hydrochloride;1-(2,3-Dichlorophenyl)ethanamine hydrochloride;1-(2,3-DICHLOROPHENYL)ETHAN-1-AMINE HYDROCHLORIDE;Tox21_500476;LP00476;AK555588;2,3-Dichloro-?-methylbenzylamine hydrochloride;1-(2,3-di

Cas No.

39959-66-5

分子式

C₈H₁₀Cl₃N

分子量

226.53

包装储存

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

生物活性

1-(2,3-Dichlorophenyl)ethanamine hydrochloride is a phenylethanolamine N-methyltransferase (PNMT) inhibitor. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride effectively reduces blood pressure of spontaneously hypertensive. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride can be used for the research of blood pressure.

性状

Solid

体内研究(In Vivo)

1-(2,3-Dichlorophenyl)ethanamine hydrochloride (50 mg/kg; i.p. once daily for three days) effects blood pressure of spontaneously hypertensive rats .

Medlife has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Adult spontaneously hypertensive rats (SHR) and Wistar Kyoto rats
Dosage:	50 mg/kg
Administration:	Intraperitoneal injection; 50 mg/kg; once daily, for 3 consecutive days
Result:	Significantly reduced of the blood pressure in spontaneously hypertensive rats, but showed no significant changes in Wistar-Kyoto rats.

运输条件

Room temperature or refrigerated transportation.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

参考文献

[1]. Saavedra JM. Adrenaline levels in brain stem nuclei and effects of a PNMT inhibitor on spontaneously hypertensive rats. Brain Res. 1979 Apr 27;166(2):283-92. [Information]

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Data Sheet

1：一般建议：溶解度为Medlife测试数据，可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解，请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异，仅做参考，具体以实验方案为准。

2：储存条件：粉末-20°C一般情况可以保存3年，溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异，请细致阅读产品信息，并辅助参考相关文献描述。

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