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α-Conotoxin MII (Synonyms: α-CTxMII)
目录号: PC16799 纯度: ≥98%
CAS No. :175735-93-0
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中文名称
α-Conotoxin MII
英文名称
α-Conotoxin MII
英文别名
alpha-conotoxin MII;alpha-conotoxin MII;alpha-MII;alpha-MII;MII;MII
Cas No.
175735-93-0
分子式
C67H103N23O22S4
分子量
1710.94
包装储存

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

生物活性

α-Conotoxin MII (α-CTxMII), a 16-amino acid peptide from the venom of the marine snail Conus magus, potently blocks nicotinic acetylcholine receptors (nAChRs) composed of α3β2 subunits, with an IC50 of 0.5 nM. α-Conotoxin MII (α-CTxMII) potently blocks β3-containing neuronal nicotinic receptors .

性状

Solid

IC50 & Target[1][2]

IC50: 0.5 nM (α3β2).

体外研究(In Vitro)

α-Conotoxin MII (0.5-3.5 nM) blocks ACh responses in oocytes expressing α3β2 nicotinic acetylcholine receptors.

Medlife has not independently confirmed the accuracy of these methods. They are for reference only.

运输条件

Room temperature or refrigerated transportation.

储存方式

Sealed storage, away from moisture and light, under nitrogen

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

SequenceShortening

GCCSNPVCHLEHSNLC-NH2 (Disulfide bridge:Cys2-Cys8;Cys3-Cys16)

Sequence

Gly-Cys-Cys-Ser-Asn-Pro-Val-Cys-His-Leu-Glu-His-Ser-Asn-Leu-Cys-NH2 (Disulfide bridge:Cys2-Cys8;Cys3-Cys16)

参考文献
搜索质检报告(COA)

1:一般建议:溶解度为Medlife测试数据,可能与文献描述存在差异。这是由于生产工艺和批次不同产生的正常现象。为了使其更好的溶解,请用37℃加热试管并在超声波水浴中震动片刻。不同批次产品溶解度各有差异,仅做参考,具体以实验方案为准。

2:储存条件:粉末-20°C一般情况可以保存3年,溶于溶剂-80°C一般情况可以保存1年。不同产品及不同批次产品可能存在差异,请细致阅读产品信息,并辅助参考相关文献描述。

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The dilution calculator equation
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